An Hyo-Jin, Choi Hyun-Myung, Park Hyeung-Suk, Han Jae-Gab, Lee Eun-Hee, Park Young-Sig, Um Jae-Young, Hong Seung-Heon, Kim Hyung-Min
College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University, Dongdaemun-Gu, Seoul, Korea.
Ann Nutr Metab. 2006;50(4):380-6. doi: 10.1159/000094303. Epub 2006 Jun 29.
BACKGROUND/AIMS: A unicellular algae, Chlorella vulgaris, was used as a biological response modifier. Although hot water extracts of C. vulgaris (CVE) are thought to augment immune responses, the effect of CVE on fatigue and physical stamina has not been studied.
In the present study, we investigated the effect of CVE on forced swimming test and blood biochemical parameters related to fatigue, blood urea nitrogen (BUN), creatine kinase (CK), lactic dehydrogenase (LDH), glucose (Glc), and total protein (TP). CVE (0.05-0.15 g/kg/day) was orally administered to mice.
After 7 days, the immobility time was decreased in the 0.1- and 0.15-g/kg CVE-treated groups (179 +/- 8.3 and 175 +/- 2.1 s) in comparison with the control group (223 +/- 5.4 s). In addition, the contents of BUN, CK, and LDH in the blood serum were decreased in the CVE-fed group. However, they had no effect on the elevation of Glc and TP level.
The results predict a potential benefit of CVE for enhancing immune function and improving physical stamina.
背景/目的：单细胞藻类普通小球藻被用作生物反应调节剂。尽管普通小球藻热水提取物（CVE）被认为可增强免疫反应，但CVE对疲劳和体力的影响尚未得到研究。
在本研究中，我们调查了CVE对强迫游泳试验以及与疲劳相关的血液生化参数的影响，这些参数包括血尿素氮（BUN）、肌酸激酶（CK）、乳酸脱氢酶（LDH）、葡萄糖（Glc）和总蛋白（TP）。将CVE（0.05 - 0.15克/千克/天）口服给予小鼠。
7天后，与对照组（223 ± 5.4秒）相比，0.1克/千克和0.15克/千克CVE处理组的不动时间减少（分别为179 ± 8.3秒和175 ± 2.1秒）。此外，CVE喂养组血清中BUN、CK和LDH的含量降低。然而，它们对Glc和TP水平的升高没有影响。
结果预示CVE在增强免疫功能和改善体力方面具有潜在益处。
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