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嗜铬细胞瘤所致高血压性原发性脑室内出血

Hypertensive primary intraventricular hemorrhage due to a phaeochromocytoma.

作者信息

Rajendra Tiruchelvarayan, Kumar Krishan, Liang Loh Hwai

机构信息

Department of Neurosurgery, National Neuroscience Institute (Singapore General Hospital Campus), Singapore.

出版信息

ANZ J Surg. 2006 Jul;76(7):664-7. doi: 10.1111/j.1445-2197.2006.03626.x.

Abstract

Primary intraventricular haemorrhage (IVH) is rare. We defined primary IVH as haemorrhage into the ventricles only as detected by computerized tomographic (CT) brain scan. This is in contrast with other intracerebral haemorrhages (e.g. basal ganglia/thalamic with intraventricular extension). The clinical condition of the patient ranges from minimal neurological deficits to coma/death. It also carries with it a poor prognosis of up to 80% when all four ventricles are involved. We present a 45-year-old Chinese female who presented with a hypertensive IVH which was managed successfully with ventricular drainage and intraventricular urokinase therapy. An adrenal phaeochromocytoma was diagnosed which was subsequently removed laparoscopically. The patient has recovered well in all aspects. This case report will discuss management of IVH and the importance of searching for secondary causes of hypertension.

摘要

原发性脑室内出血(IVH)较为罕见。我们将原发性IVH定义为仅通过脑部计算机断层扫描(CT)检测到的脑室内出血。这与其他脑内出血(例如伴有脑室内扩展的基底节/丘脑出血)形成对比。患者的临床状况从轻微神经功能缺损到昏迷/死亡不等。当四个脑室均受累时,其预后也很差,死亡率高达80%。我们报告一名45岁中国女性,她因高血压性IVH就诊,通过脑室引流和脑室内尿激酶治疗成功治愈。随后诊断出肾上腺嗜铬细胞瘤,并通过腹腔镜手术将其切除。患者各方面恢复良好。本病例报告将讨论IVH的治疗以及寻找高血压继发原因的重要性。

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