Mardini Samir, Chang Yang-Ming, Tsai Chi-Ying, Coskunfirat O Koray, Wei Fu-Chan
Department of Plastic Surgery, Chang Gung Memorial Hospital, and the Medical College, Chang Gung University, Taipei, Taiwan.
Plast Reconstr Surg. 2006 Jul;118(1):102-7. doi: 10.1097/01.prs.0000221118.31863.c4.
Oral cancer patients receive wide excision of oral structures and reconstruction of the intraoral defects with skin grafts and/or local, regional, or free flaps. Trismus is a common postoperative sequela, even without postoperative radiotherapy. Trismus decreases patients' quality of life and can have detrimental effects on their oral hygiene and nutritional status.
Between May of 1999 and June of 2003, 11 patients were operated on for release of trismus and reconstruction after previous intraoral reconstructions. The patients had been reconstructed with skin grafts (n = 4), radial forearm flaps (n = 3), anterolateral thigh flaps (n = 1), artificial dermis (n = 1), radial forearm flaps with skin grafts (n = 1), and pedicled pectoralis major flaps with skin grafts (n = 1). Eight patients had received postoperative radiotherapy. The patients presented with a mean interincisal distance of 3.1 mm (range, 0 to 10 mm).
After trismus release, the intraoral soft-tissue defects were reconstructed with one or two free flaps (six anterolateral thigh flaps, nine forearm flaps, and one fibula osteoseptocutaneous flap). Fifteen of the 16 flaps were successful, with one flap failure. Average interincisal distance was 33.4 mm immediately after the release (range, 27 to 35 mm) and 18.9 mm (range, 5 to 30 mm) at a mean follow-up time of 22.7 months (16.1 mm in the radiated group and 26.3 mm in the nonradiated group). The mean amount of improvement was 15.8 mm.
The use of free flaps to reconstruct the defects created after trismus release in patients with previous intraoral reconstruction is a viable option that yields reasonable, long-lasting improvements in mouth opening, intraoral hygiene, and quality of life.
口腔癌患者需对口腔结构进行广泛切除,并采用皮肤移植和/或局部、区域或游离皮瓣修复口腔内缺损。牙关紧闭是常见的术后后遗症,即使术后未进行放疗也是如此。牙关紧闭会降低患者的生活质量,并对其口腔卫生和营养状况产生不利影响。
1999年5月至2003年6月期间,11例患者接受了牙关紧闭松解及先前口腔内重建术后的修复手术。这些患者曾采用皮肤移植(n = 4)、桡侧前臂皮瓣(n = 3)、股前外侧皮瓣(n = 1)、人工真皮(n = 1)、带皮肤移植的桡侧前臂皮瓣(n = 1)以及带皮肤移植的带蒂胸大肌皮瓣(n = 1)进行重建。8例患者接受了术后放疗。患者的平均切牙间距离为3.1毫米(范围为0至10毫米)。
在牙关紧闭松解后,用一或两个游离皮瓣修复口腔内软组织缺损(六个股前外侧皮瓣、九个前臂皮瓣和一个腓骨骨膜皮瓣)。16个皮瓣中有15个成功,1个皮瓣失败。松解后即刻平均切牙间距离为33.4毫米(范围为27至35毫米),平均随访22.7个月时为18.9毫米(范围为5至30毫米)(放疗组为16.1毫米,未放疗组为26.3毫米)。平均改善量为15.8毫米。
对于先前口腔内已重建的患者,使用游离皮瓣修复牙关紧闭松解后产生的缺损是一种可行的选择,可在开口度、口腔卫生和生活质量方面产生合理且持久的改善。