O'Connor R Corey, Nanigian Dana K, Lyon Mark B, Ellison Lars M, Bales Gregory T, Stone Anthony R
Department of Urology, University of California Davis Medical Center, Sacramento, California 95817, USA.
Neurourol Urodyn. 2006;25(7):685-8. doi: 10.1002/nau.20286.
To assess the early results of mid-urethral slings placed via the transobturator approach (TVT-O) for stress urinary incontinence (SUI) in women with high (>60 cm H(2)O) and low (<or=60 cm H(2)O) valsalva leak point pressure (VLPP).
Forty-three women with urodynamically proven SUI underwent TVT-O. Patients were divided into either high (>60 cm H(2)O) or low (<or=60 cm H(2)O) VLPP categories based on preoperative urodynamic studies. Patient outcomes were assessed based on degree of postoperative SUI as either dry (no pads, no SUI), or wet (any leakage). Follow-up visits were at 1, 6, 12, and 24 weeks.
Overall, 65% (28/43) women were cured following TVT-O for SUI. When stratified based on preoperative VLPP, 77% (24/31) of patients with VLPP greater than 60 were cured while only 25% (3/12) of patients with VLPP less than or equal to 60 were cured. No intraoperative complications were noted. The odds of continued SUI following TVT-O were 12 times greater for women with VLPP <or=60 compared to those with VLPP >60.
With limited follow up, TVT-O appears to be a safe and effective surgical treatment for female SUI producing excellent results in patients with VLPP >60 cm/H(2)0. Patients with low VLPP may consider conventional, retropubic mid-urethral slings or other procedures as treatment for SUI.
评估经闭孔途径(TVT - O)放置的中段尿道吊带术治疗膀胱颈漏尿点压(VLPP)高(>60 cm H₂O)和低(≤60 cm H₂O)的女性压力性尿失禁(SUI)的早期效果。
43例经尿动力学证实为SUI的女性接受了TVT - O手术。根据术前尿动力学研究,将患者分为高(>60 cm H₂O)或低(≤60 cm H₂O)VLPP组。根据术后SUI程度评估患者结局,分为干爽(无需使用尿垫,无SUI)或潮湿(有任何漏尿)。随访时间为1、6、12和24周。
总体而言,TVT - O治疗SUI后65%(28/43)的女性治愈。根据术前VLPP分层时,VLPP大于60的患者中有77%(24/31)治愈,而VLPP小于或等于60的患者中只有25%(3/12)治愈。未观察到术中并发症。与VLPP >60的女性相比,VLPP≤60的女性TVT - O术后持续存在SUI的几率高12倍。
随访有限的情况下,TVT - O似乎是治疗女性SUI的一种安全有效的手术方法,对VLPP >60 cm/H₂O的患者效果极佳。VLPP低的患者可考虑采用传统的耻骨后中段尿道吊带术或其他手术方法治疗SUI。