Rosenthal David I, Asper Joshua A, Barker Jerry L, Garden Adam S, Chao K S Clifford, Morrison William H, Weber Randal S, Ang K Kian
Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
Head Neck. 2006 Nov;28(11):967-73. doi: 10.1002/hed.20446.
When quality assurance programs in clinical radiation oncology focus mainly on the technical aspects of treatment, they tend to underplay questions of therapeutic process and outcome. We determined the value of clinical peer review in radiation therapy for head and neck cancer that involved head and neck examination.
Data were collected prospectively on 134 consecutive patients with preliminary radiation therapy (RT) plans. Peer review was performed that included head and neck examination and imaging review to confirm target localization.
Peer review led to changes in treatment plans for 66% of patients. Most changes were minor, but 11% of changes were major and thought to be of a magnitude that could potentially affect therapeutic outcome or normal tissue toxicity. Most changes involved target delineation based on physical findings
Peer review of radiation target localization in RT plans led to changes that could potentially affect rates of cancer control or complication in about 10% of patients. We suggest that the accuracy of head and neck radiation oncology treatment plans might be increased by co-examination by another head and neck cancer specialist, typically a radiation oncologist or head and neck surgeon, to confirm RT target volumes.
当临床放射肿瘤学的质量保证计划主要关注治疗的技术方面时,它们往往会忽视治疗过程和结果的问题。我们确定了涉及头颈检查的头颈癌放射治疗中临床同行评审的价值。
前瞻性收集了134例连续患者的初步放射治疗(RT)计划数据。进行了同行评审,包括头颈检查和影像检查以确认靶区定位。
同行评审导致66%的患者治疗计划发生改变。大多数改变较小,但11%的改变较大,被认为可能会影响治疗结果或正常组织毒性。大多数改变涉及基于体格检查结果的靶区勾画。
对RT计划中的放射靶区定位进行同行评审导致约10%的患者发生可能影响癌症控制率或并发症的改变。我们建议,通过另一位头颈癌专家(通常是放射肿瘤学家或头颈外科医生)共同检查以确认RT靶区体积,可能会提高头颈放射肿瘤学治疗计划的准确性。