成功的转运蛋白会增强自我意识。
Successful transporter gets an EGO boost.
作者信息
Piper Robert C
机构信息
Department of Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242.
出版信息
Dev Cell. 2006 Jul;11(1):6-7. doi: 10.1016/j.devcel.2006.06.008.
PMID:16824948
Abstract
The trafficking of nutrient transporters is highly regulated and controlled by a variety of signal transduction pathways. A recent study by in Nature Cell Biology demonstrates a role for a novel GTPase-containing complex that allows the amino acid permease Gap1 to recycle out of late endosomal compartments. This complex is likely to play critical roles in allowing animal cells to mobilize their nutrient transporters in response to metabolic demands.
摘要
营养转运蛋白的运输受到多种信号转导途径的高度调控。《自然·细胞生物学》最近的一项研究表明，一种新型的含GTP酶复合物具有重要作用，它能使氨基酸通透酶Gap1从晚期内体区室中循环出来。这种复合物可能在使动物细胞根据代谢需求调动其营养转运蛋白方面发挥关键作用。
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