Noble Simon I R, Finlay Ilora G
Cardiff University, Velindre Hospital, Cardiff, Wales, UK.
J Pain Symptom Manage. 2006 Jul;32(1):38-43. doi: 10.1016/j.jpainsymman.2005.11.013.
Palliative care patients are highly prothrombotic, yet there are no national guidelines for the prevention of venous thromboembolism (VTE). A survey was undertaken to explore thromboprophylaxis practice within British palliative care inpatient units and whether it changed over 5 years in keeping with emerging evidence. A descriptive semistructured telephone survey was conducted in April, 2000 and March, 2005 to explore current thromboprophylaxis practice. Seventy-four percent of units participated in 2000 and 91% participated in 2005. Units surveyed in 2000 revealed that 2% had thromboprophylaxis guidelines and up to 75% would stop ongoing low molecular weight heparin (LMWH) in a highly prothrombotic, good prognosis inpatient. The survey in 2005 indicated that thromboprophylaxis guidelines were being developed in 19% of units and only 18% of units surveyed would stop LMWH in a patient already receiving thromboprophylaxis (P < 0.001). There appears to be a growing awareness of the problem of VTE in British palliative care inpatients, as evidenced by changes in attitudes and practice. Reasons for this are discussed.
姑息治疗患者具有高血栓形成倾向,但目前尚无预防静脉血栓栓塞(VTE)的全国性指南。一项调查旨在探究英国姑息治疗住院病房的血栓预防措施,以及这些措施在5年中是否根据新出现的证据有所变化。2000年4月和2005年3月进行了一项描述性半结构式电话调查,以探究当前的血栓预防措施。2000年有74%的病房参与调查,2005年有91%参与。2000年接受调查的病房显示,2%有血栓预防指南,高达75%会在血栓形成倾向高、预后良好的住院患者中停用正在使用的低分子量肝素(LMWH)。2005年的调查表明,19%的病房正在制定血栓预防指南,接受调查的病房中只有18%会在已经接受血栓预防的患者中停用LMWH(P<0.001)。英国姑息治疗住院患者对VTE问题的认识似乎在不断提高,态度和做法的变化就是证明。文中讨论了其原因。