Mann Balwinder Singh, Wormald Peter John
Department of Surgery-Otolaryngology Head & Neck Surgery, Adelaide and Flinders Universities, South Australia, Australia.
Laryngoscope. 2006 Jul;116(7):1172-4. doi: 10.1097/01.mlg.0000218099.33523.19.
Dacryocystorhinostomy (DCR) is currently regarded as the treatment of choice for treatment of epiphora resulting from blockage at the level of the nasolacrimal duct. There has been debate on the effect of healing on the size of the DCR ostium after surgery. The aim of this study is to determine how the size of the surgically created lacrimal ostium changes over time.
The authors conducted a prospective cohort study of unselected patients who underwent DCR from March 1999 to November 2004.
Thirty-eight patients who underwent intranasal DCR were analyzed. There were 14 males and 24 females with 11 patients undergoing bilateral DCR, resulting in 49 endoscopic intranasal DCRs being analyzed. The endoscopic findings of the size of the ostia were recorded at the time of surgery and at 4 weeks, 6 months, and 12 months after surgery. There were 33 DCRs reviewed at 12 months and 16 reviewed at 6 months who did not reattend for their 12-month appointment. Analysis of variance was used to compare the difference in the ostium sizes at the end of surgery and at 4 weeks, 6 months, and 12 months after surgery.
The male to female ratio was 1:1.7 and the average age was 64.5 (standard deviation [SD]=17.8 years). The ostium measured 11.8 (STD=2.3, 95% confidence interval [CI]=11.1-12.5)x7.2 (SD=1.7; 95% CI=6.7-7.7) at the time of surgery and 10.1 (SD=2.3; 95% CI=9.3-10.9)x6.4 (SD=1.3; 95% CI=6.0-6.9) at 4 weeks, 9.8 (SD=2.5; 95% CI=9.0-10.6)x6.5 (SD=1.5; 95% CI=6.0-6.9) at 6 months, and 10.1 (SD=2.5; 95% CI=9.2-11.0)x6.6 (SD=1.6; 95% CI=6.0-7.1) at 12 months. Statistical analysis (analysis of variance) showed a significant shrinkage from surgery to 4 weeks but no statistical difference from 4 weeks to 6 or 12 months.
The DCR ostium shrinks a small but significant amount in the first 4 weeks after surgery. Thereafter, the ostium size appears to be stable. We propose that the surgical technique used in which the nasal and lacrimal mucosa is approximated results in a first intention healing with minimal ostial granulation tissue and stenosis and minimal shrinkage of the postoperative DCR ostium.
目前,泪囊鼻腔吻合术(DCR)被视为治疗鼻泪管阻塞所致溢泪的首选治疗方法。术后愈合对DCR造口大小的影响一直存在争议。本研究的目的是确定手术创建的泪造口大小如何随时间变化。
作者对1999年3月至2004年11月接受DCR的未选患者进行了一项前瞻性队列研究。
对38例行鼻内DCR的患者进行分析。其中男性14例,女性24例,11例患者接受双侧DCR,共分析49例鼻内镜下鼻内DCR。在手术时以及术后4周、6个月和12个月记录造口大小的内镜检查结果。12个月时对33例DCR进行了复查,6个月时对16例进行了复查,这些患者未再次前来进行12个月的复诊。采用方差分析比较手术结束时以及术后4周、6个月和12个月造口大小的差异。
男女比例为1:1.7,平均年龄为64.5岁(标准差[SD]=17.8岁)。手术时造口大小为11.8(STD=2.3,95%置信区间[CI]=11.1-12.5)×7.2(SD=1.7;95%CI=6.7-7.7),4周时为10.1(SD=2.3;95%CI=9.3-10.9)×6.4(SD=1.3;95%CI=6.0-6.9),6个月时为9.8(SD=。
DCR造口在术后前4周会有少量但显著的缩小。此后,造口大小似乎稳定。我们认为所采用的手术技术使鼻黏膜和泪黏膜贴合,从而实现一期愈合,造口肉芽组织和狭窄最少,术后DCR造口缩小最小。