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本文引用的文献
1
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Acta Crystallogr Sect E Struct Rep Online. 2006 Jul;62(7):o2815-o2816. doi: 10.1107/S1600536806021817.
2
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Life Sci. 2003 Jun 27;73(6):691-8. doi: 10.1016/s0024-3205(03)00389-8.
3
Guanidinium and aminoimidazolinium derivatives of N-(4-piperidyl)propanamides as potential ligands for mu opioid and I2-imidazoline receptors: synthesis and pharmacological screening.
Bioorg Med Chem. 2002 Apr;10(4):1009-18. doi: 10.1016/s0968-0896(01)00356-x.
4
Biological activity of fragments and analogues of the potent dimeric opioid peptide, biphalin.
Bioorg Med Chem Lett. 1999 Sep 20;9(18):2763-6. doi: 10.1016/s0960-894x(99)00464-3.
5
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Bioorg Med Chem Lett. 1998 Sep 22;8(18):2563-8. doi: 10.1016/s0960-894x(98)00456-9.
6
Adverse effects of opioid agonists and agonist-antagonists in anaesthesia.
Drug Saf. 1998 Sep;19(3):173-89. doi: 10.2165/00002018-199819030-00002.
7
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J Pharmacol Exp Ther. 1993 Aug;266(2):577-84.
8
Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier.
Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7114-8. doi: 10.1073/pnas.91.15.7114.
9
Synthesis and evaluation of 1- and 2-substituted fentanyl analogues for opioid activity.
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