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冠状动脉搭桥手术中桡动脉血管桥的转归

The fate of the radial artery conduit in coronary artery bypass grafting surgery.

作者信息

Nezić Dusko G, Knezević Aleksandar M, Milojević Predrag S, Dukanović Bosko P, Jović Miomir D, Borzanović Milorad D, Nesković Aleksandar N

机构信息

Dedinje Cardiovascular Institute, M. Tepića 1, 11040 Belgrade, Serbia and Montenegro.

出版信息

Eur J Cardiothorac Surg. 2006 Aug;30(2):341-6. doi: 10.1016/j.ejcts.2006.05.012. Epub 2006 Jul 7.

Abstract

Coronary artery bypass grafting (CABG) is the standard surgical procedure for the treatment of advanced coronary artery disease. CABG surgery has been demonstrated to improve symptoms and, in specific subgroups of patients, to prolong life. Despite its success, the long-term outcome of coronary bypass surgery is strongly influenced by the fate of the vascular conduits used. Impressive long-term disease-free patency rate of the left internal thoracic artery-left anterior descending coronary artery (LITA-LAD) graft, coupled with proven long-term survival benefits, has led to its becoming a 'golden standard' of CABG. Previous long-term studies have also shown unsatisfactory patency of saphenous vein grafts used for myocardial revascularization, compared with internal thoracic artery grafts. Thus, the use of arterial conduits has expanded beyond the internal thoracic arteries (ITAs) to include the right gastroepiploic artery, the inferior epigastric artery, and the radial artery. The assumption is that although the performance of one or two arterial ITA graft is superb, more arterial grafts should perform better in the long-term follow-up. Several studies concerning the use of the radial artery bypass grafts have documented excellent clinical results and satisfactory short-term as well as mid-term patency rates at restudy angiography, supporting its continued use as a bypass conduit. However, a note of caution concerning radial artery conduit patency rate have appeared in few recent reports. Thus, in this paper, we summarize the current evidence about the radial artery as a conduit in CABG surgery, with special emphasis on the clinical results.

摘要

冠状动脉旁路移植术(CABG)是治疗晚期冠状动脉疾病的标准外科手术。CABG手术已被证明可改善症状,并且在特定亚组患者中可延长寿命。尽管取得了成功,但冠状动脉搭桥手术的长期结果仍受到所用血管移植物命运的强烈影响。左胸廓内动脉-左前降支冠状动脉(LITA-LAD)移植物令人印象深刻的长期无病通畅率,再加上已证实的长期生存益处,使其成为CABG的“金标准”。先前的长期研究还表明,与胸廓内动脉移植物相比,用于心肌血运重建的大隐静脉移植物的通畅率并不理想。因此,动脉移植物的使用已从胸廓内动脉(ITA)扩展到包括右胃网膜动脉、腹壁下动脉和桡动脉。人们认为,尽管一两个ITA动脉移植物的表现非常出色,但更多的动脉移植物在长期随访中应该表现得更好。几项关于桡动脉旁路移植物使用的研究记录了出色的临床结果以及复查血管造影时令人满意的短期和中期通畅率,支持其继续作为旁路管道使用。然而,最近有少数报告对桡动脉管道的通畅率提出了警告。因此,在本文中,我们总结了关于桡动脉作为CABG手术中管道的当前证据,特别强调临床结果。

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