通过分子内衣笠反应合成β-内酰胺稠合环状烯二炔的新方法。

A novel synthesis of beta-lactam fused cyclic enediynes by intramolecular Kinugasa reaction.

作者信息

Pal Runa, Basak Amit

机构信息

Bioorganic Laboratory, Department of Chemistry, Indian Institute of Technology, Kharagpur, India.

出版信息

Chem Commun (Camb). 2006 Jul 28(28):2992-4. doi: 10.1039/b605743h. Epub 2006 Jun 7.

DOI:10.1039/b605743h

PMID:16832514

Abstract

A general synthetic route to beta-lactam-fused enediynes by intramolecular Kinugasa reaction has been successfully developed. The method has widened the scope of Kinugasa reaction in the synthesis of sensitive systems like the one described in this communication.

摘要

通过分子内的衣笠反应合成β-内酰胺稠合烯二炔的通用合成路线已成功开发。该方法拓宽了衣笠反应在合成如本通讯中所述的敏感体系方面的应用范围。