[Prostaglandins and damage to the gastric mucosa].

The author critically analyses the involvement of prostaglandins in peptic ulceration. Clinical evidence suggests that for the treatment of peptic ulcer other available drugs (e.g. H2-blockers) are as effective and have fewer side-effects. A potential role in prevention of drug induced gastric mucosal damage (NSAID, ASA) may be verified in further studies.