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急性腹主动脉瘤:血流动力学稳定患者血管内修复术与开放手术的成本分析及1年随访

Acute abdominal aortic aneurysms: cost analysis of endovascular repair and open surgery in hemodynamically stable patients with 1-year follow-up.

作者信息

Visser Jacob J, van Sambeek Marc R H M, Hunink M G Myriam, Redekop W Ken, van Dijk Lukas C, Hendriks Johanna M, Bosch Johanna L

机构信息

Departments of Epidemiology and Biostatistics, Radiology, and Surgery, Erasmus Medical Center, Room Ee21-40B, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands.

出版信息

Radiology. 2006 Sep;240(3):681-9. doi: 10.1148/radiol.2403051005. Epub 2006 Jul 12.

Abstract

PURPOSE

To retrospectively assess the in-hospital and 1-year follow-up costs of endovascular aneurysm repair and conventional open surgery in patients with acute infrarenal abdominal aortic aneurysm (AAA) by using a resource-use approach.

MATERIALS AND METHODS

Institutional Review Board approval was obtained, and informed consent was waived. In-hospital costs for all consecutive patients (61 men, six women; mean age, 72.0 years) who underwent endovascular repair (n = 32) or open surgery (n = 35) for acute infrarenal AAA from January 1, 2001, to December 31, 2004, were assessed by using a resource-use approach. Patients who did not undergo computed tomography before the procedure were excluded from analysis. One-year follow-up costs were complete for 30 patients who underwent endovascular repair and for 34 patients who underwent open surgery. Costs were assessed from a health care perspective. Mean costs were calculated for each treatment group and were compared by using the Mann-Whitney U test (alpha = .05). The influence of clinical variables on the total in-hospital cost was investigated by using univariate and multivariate analyses. Costs were expressed in euros for the year 2003.

RESULTS

Sex, age, and comorbidity did not differ between treatment groups (P > .05). The mean total in-hospital costs were lower for patients who underwent endovascular repair than for those who underwent open surgery (euro20 767 vs euro35 470, respectively; P = .004). The total costs, including those for 1-year follow-up, were euro23 588 for patients who underwent endovascular repair and euro36 448 for those who underwent open surgery (P = .05). The results of multivariate analysis indicated that complications had a significant influence on total in-hospital cost; patients who had complications incurred total in-hospital costs that were 2.27 times higher than those for patients who had no complications.

CONCLUSION

Total in-hospital costs and total overall costs, which included 1-year follow-up costs, were lower in patients with acute AAA who underwent endovascular repair than in those who underwent open surgery.

摘要

目的

采用资源利用方法,回顾性评估急性肾下腹主动脉瘤(AAA)患者接受血管内动脉瘤修复术和传统开放手术的住院费用及1年随访费用。

材料与方法

获得机构审查委员会批准,豁免知情同意书。采用资源利用方法评估2001年1月1日至2004年12月31日期间因急性肾下AAA接受血管内修复术(n = 32)或开放手术(n = 35)的所有连续患者(61名男性,6名女性;平均年龄72.0岁)的住院费用。术前未进行计算机断层扫描的患者被排除在分析之外。30例接受血管内修复术的患者和34例接受开放手术的患者完成了1年随访费用评估。从医疗保健角度评估费用。计算每个治疗组的平均费用,并使用Mann-Whitney U检验(α = 0.05)进行比较。采用单因素和多因素分析研究临床变量对住院总费用的影响。费用以2003年的欧元表示。

结果

治疗组之间的性别、年龄和合并症无差异(P > 0.05)。接受血管内修复术的患者的平均住院总费用低于接受开放手术的患者(分别为20767欧元和35470欧元;P = 0.004)。包括1年随访费用在内的总费用,接受血管内修复术的患者为23588欧元,接受开放手术的患者为36448欧元(P = 0.05)。多因素分析结果表明并发症对住院总费用有显著影响;发生并发症的患者的住院总费用比未发生并发症的患者高2.27倍。

结论

接受血管内修复术的急性AAA患者的住院总费用和包括1年随访费用在内的总费用低于接受开放手术的患者。

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