Ratcliff J Robyn, Naqvi Asghar, de la Roza Gustavo, Strauss Judith A, Damron Timothy A
Department of Orthopedic Surgery, Upstate Medical University, State University of New York at Syracuse, Syracuse, NY 13210, USA.
Ann Diagn Pathol. 2006 Aug;10(4):222-9. doi: 10.1016/j.anndiagpath.2005.12.006.
Surface lesions of bone usually present little diagnostic dilemma because the majority are conventional osteochondromas. Other surface bone lesions include periosteal chondroma, periosteal chondrosarcoma, and parosteal osteosarcoma. Mineralized soft tissue lesions such as myositis ossificans, synovial chondroma, and synovial sarcoma may present in a similar fashion when they occur in a juxtaarticular position. The soft tissue osteochondroma or paraarticular osteochondroma may simulate some of these more aggressive tumors, and its recognition is important to avoid overtreatment. A case of an 11-year-old male with a soft tissue osteochondroma is reported to illustrate the characteristic radiographic and histological features of this rare entity. No prior reports have examined soft tissue osteochondroma for expression of parathyroid hormone related protein, an established cartilage tumor proliferative mitogen.
骨表面病变通常很少带来诊断难题，因为大多数是传统的骨软骨瘤。其他骨表面病变包括骨膜软骨瘤、骨膜软骨肉瘤和骨旁骨肉瘤。矿化的软组织病变，如骨化性肌炎、滑膜软骨瘤和滑膜肉瘤，当其发生在关节周围位置时，可能以类似的方式表现。软组织骨软骨瘤或关节旁骨软骨瘤可能会模拟一些这些更具侵袭性的肿瘤，识别它对于避免过度治疗很重要。报告了一例11岁男性患有软组织骨软骨瘤的病例，以说明这种罕见实体的特征性影像学和组织学特征。此前没有报告检测过软组织骨软骨瘤中甲状旁腺激素相关蛋白的表达，甲状旁腺激素相关蛋白是一种已确定的软骨肿瘤增殖有丝分裂原。
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