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感染人类免疫缺陷病毒(HIV)和未感染HIV的退伍军人中的酒精问题与医疗服务利用情况

Alcohol problems and health care services use in human immunodeficiency virus (HIV)-infected and HIV-uninfected veterans.

作者信息

Kraemer Kevin L, McGinnis Kathleen A, Skanderson Melissa, Cook Robert, Gordon Adam, Conigliaro Joseph, Shen Yujing, Fiellin David A, Justice Amy C

机构信息

Center for Research on Health Care, Division of General Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

出版信息

Med Care. 2006 Aug;44(8 Suppl 2):S44-51. doi: 10.1097/01.mlr.0000223703.91275.78.

Abstract

BACKGROUND

Although alcohol problems are common in human immunodeficiency virus (HIV)-infected patients, their impact on health care services use in HIV-infected patients is not well understood.

OBJECTIVE

We sought to examine the association between alcohol problems and health care services use in HIV-infected and HIV-uninfected patients.

DESIGN, SETTING, AND SUBJECTS: We undertook a prospective analysis of 16,048 HIV-infected veterans and 32,096 age-, race-, gender-, and region-matched HIV-uninfected controls identified through the national Veterans Affairs electronic administrative medical record database. We identified subjects with alcohol problems using ICD-9-CM codes for alcohol diagnoses and/or alcohol-related complications.

MAIN OUTCOME MEASURES

We measured outpatient visits, emergency department visits, and inpatient hospitalizations over 12 months of follow-up.

RESULTS

In adjusted analyses, HIV-infected veterans with alcohol problems were significantly more likely than HIV-uninfected veterans without alcohol problems to have at least 1 outpatient visit and at least 1 inpatient hospitalization and, among those with any health services use, to have significantly greater rates for outpatient visits (Incidence rate ratio [IRR] 2.17; 95% confidence interval [CI] 2.06-2.28; P < 0.001), emergency department visits (IRR 1.46; 95% CI 1.35-1.58; P < 0.001), and inpatient hospitalizations (IRR 1.46; 95% CI 1.30-1.64; P < 0.001). The incidence rates for outpatient visits, mental health visits, emergency department visits, and inpatient hospitalizations were significantly higher in HIV-infected veterans with alcohol problems than in HIV-infected veterans without alcohol problems. We did not find a consistent interaction effect between alcohol problems and HIV status.

CONCLUSION

Alcohol problems are associated with greater outpatient, emergency department, and inpatient health care utilization in HIV-infected and HIV-uninfected veterans. However, alcohol does not appear to have a stronger effect on health services use in HIV-infected veterans compared with HIV-uninfected veterans.

摘要

背景

尽管酒精问题在感染人类免疫缺陷病毒(HIV)的患者中很常见,但它们对HIV感染患者医疗服务使用的影响尚不清楚。

目的

我们试图研究酒精问题与HIV感染患者和未感染HIV患者医疗服务使用之间的关联。

设计、地点和研究对象:我们对通过国家退伍军人事务电子行政病历数据库确定的16048名感染HIV的退伍军人和32096名年龄、种族、性别和地区匹配的未感染HIV的对照进行了前瞻性分析。我们使用国际疾病分类第九版临床修订本(ICD-9-CM)代码来识别患有酒精问题的受试者,这些代码用于酒精诊断和/或与酒精相关的并发症。

主要观察指标

我们测量了随访12个月期间的门诊就诊、急诊科就诊和住院情况。

结果

在调整分析中,有酒精问题的感染HIV的退伍军人比没有酒精问题的未感染HIV的退伍军人更有可能至少进行1次门诊就诊和至少1次住院治疗,并且在使用任何医疗服务的人群中,门诊就诊率(发病率比[IRR]2.17;95%置信区间[CI]2.06-2.28;P<0.001)、急诊科就诊率(IRR 1.46;95%CI 1.35-1.58;P<0.001)和住院率(IRR 1.46;95%CI 1.30-1.64;P<0.001)显著更高。有酒精问题的感染HIV的退伍军人的门诊就诊、心理健康就诊、急诊科就诊和住院的发病率显著高于没有酒精问题的感染HIV的退伍军人。我们没有发现酒精问题与HIV状态之间存在一致的交互作用。

结论

酒精问题与感染HIV和未感染HIV的退伍军人更多地使用门诊、急诊科和住院医疗服务相关。然而,与未感染HIV的退伍军人相比,酒精对感染HIV的退伍军人医疗服务使用的影响似乎并不更强。

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