Turbin Roger E, Wladis Edward J, Frohman Larry P, Langer Paul D, Kennerdell John S
Institute of Ophthalmology and Visual Science, Department of Ophthalmology, UMDNJ - New Jersey Medical School, Newark, New Jersey 07103, USA.
Ophthalmic Plast Reconstr Surg. 2006 Jul-Aug;22(4):278-82. doi: 10.1097/01.iop.0000225420.06323.76.
To describe a role for optic nerve decompression as adjuvant surgical therapy in the management of optic nerve sheath meningioma in patients with severe, progressive visual loss and optic disc edema before or after radiation therapy.
Interventional case report.
Two patients with unilateral optic nerve sheath meningioma had progressive visual loss (20/200 and no light perception) and disc edema. The first had previously undergone fractionated stereotactic radiotherapy and the second subsequently was treated with fractionated stereotactic radiotherapy after decompression surgery. After excision of a dural window and biopsy of the tumor from the nerve sheath, visual acuity improved to 20/25 and 20/200, respectively, both coinciding with resolution of disc edema.
In patients with optic nerve sheath meningioma with severe disc edema and rapid vision loss, surgery may serve an important but restricted, adjuvant role to radiation therapy under special conditions.
描述视神经减压作为辅助手术治疗在放射治疗前或后患有严重、进行性视力丧失和视盘水肿的视神经鞘膜瘤患者管理中的作用。
介入性病例报告。
两名单侧视神经鞘膜瘤患者出现进行性视力丧失(分别为20/200和无光感)和视盘水肿。第一名患者先前接受了分次立体定向放射治疗,第二名患者在减压手术后随后接受了分次立体定向放射治疗。在切除硬脑膜窗口并从神经鞘进行肿瘤活检后,视力分别提高到20/25和20/200,两者均与视盘水肿的消退同时出现。
在患有严重视盘水肿和快速视力丧失的视神经鞘膜瘤患者中,手术在特殊情况下可能对放射治疗起到重要但有限的辅助作用。