Burri Haran, Noble Stéphane, Sunthorn Henri, Dorsaz Pierre-André, Vieira Isabelle, Shah Dipen
Cardiology Service, University Hospital, 23, Micheli-du-Crest, 1211 Geneva, Switzerland.
Int J Cardiol. 2007 Apr 25;117(2):211-3. doi: 10.1016/j.ijcard.2006.05.006. Epub 2006 Jul 21.
VDD pacemakers may be implanted in the setting of atrioventricular block with preserved sinus function. Their main advantage over DDD pacemakers is use of a single lead. However, low-amplitude atrial electrograms (EGMs) recorded from the free-floating atrial electrode may lead to undersensing. There is currently no way of predicting EGM amplitude prior to implantation and to thus identify candidates who may be safely implanted with a VDD pacemaker.
We sought to investigate whether the P-wave amplitude measured on the standard surface ECG correlates with the atrial EGM amplitude measured by the single-pass lead at implantation.
Data on 122 patients implanted with a VDD pacemaker at our institution were reviewed. Atrial EGM amplitudes measured at implantation by the single-pass lead were correlated with the maximal P-wave amplitude on the surface ECG recorded just prior to implantation.
There was a highly significant correlation between the maximal P-wave amplitude on the surface ECG and the atrial EGM (Pearson's correlation 0.313, P<0.001). Multivariate analysis showed that maximal P-wave amplitude was independently associated with atrial EGM amplitude (p=0.003). For the overall population, an EGM amplitude of <0.9 mV was present in only 11/122 (9%) cases. An atrial EGM amplitude of <0.9 mV was found in 10/69 (14%) of patients with a maximal surface P-wave < or =0.1 mV but only in 1/53 (2%) of those with >0.1 mV (p=0.023).
Low-amplitude atrial EGMs at implantation are found in a minority of patients with single-pass leads. However, patients with a maximal surface P-wave amplitude of >0.1 mV are especially unlikely to have a low atrial EGM amplitude and may be good candidates for a VDD pacemaker.
VDD起搏器可植入窦房结功能正常的房室传导阻滞患者体内。与DDD起搏器相比,其主要优势在于使用单根电极导线。然而,从自由漂浮的心房电极记录到的低振幅心房电图(EGM)可能导致感知不足。目前,在植入前尚无预测EGM振幅的方法,因此无法识别可安全植入VDD起搏器的患者。
我们试图研究标准体表心电图上测量的P波振幅是否与植入时单根电极导线测量的心房EGM振幅相关。
回顾了在我院植入VDD起搏器的122例患者的数据。将植入时单根电极导线测量的心房EGM振幅与植入前记录的体表心电图上的最大P波振幅进行相关性分析。
体表心电图上的最大P波振幅与心房EGM之间存在高度显著的相关性(Pearson相关性为0.313,P<0.001)。多因素分析显示,最大P波振幅与心房EGM振幅独立相关(p=0.003)。在总体人群中,只有11/122(9%)的病例EGM振幅<0.9mV。在最大体表P波≤0.1mV的患者中,10/69(14%)的患者心房EGM振幅<0.9mV,而在最大体表P波>0.1mV的患者中,只有1/53(2%)的患者心房EGM振幅<0.9mV(p=0.023)。
在少数使用单根电极导线的患者中,植入时会出现低振幅心房EGM。然而,最大体表P波振幅>0.1mV的患者尤其不太可能出现低心房EGM振幅,可能是VDD起搏器的良好候选者。