Zhang Xiaoming, Greenleaf James F
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.
Ultrasonics. 2006 Dec 22;44 Suppl 1:e169-72. doi: 10.1016/j.ultras.2006.06.056. Epub 2006 Jul 7.
Pulse wave velocity (PWV) is widely used for estimating the stiffness of an artery. PWV is an average measurement of artery stiffness between two measuring sites. From measured PWV, the diameter and thickness are needed to calculate the elastic modulus of the artery. In this paper a new method of using ring resonant mode for estimation of arterial elastic modulus is proposed. To generate the ring resonance, a localized radiation force of ultrasound is remotely and non-invasively applied at the artery. The vibration response of the artery is measured by optical techniques. Three ring resonant modes are identified for estimation of the elastic modulus. The viscoelasticity and the complex modulus of the artery can be obtained. Experiments were carried out on a porcine artery embedded in gelatin. The estimation only requires the diameter of the artery, but does not need the thickness of the artery which is difficult to measure with accuracy and precision.
脉搏波速度（PWV）被广泛用于评估动脉的僵硬度。PWV是两个测量点之间动脉僵硬度的平均测量值。要从测量得到的PWV计算动脉的弹性模量，需要知道动脉的直径和厚度。本文提出了一种利用环形共振模式来估计动脉弹性模量的新方法。为了产生环形共振，通过超声的局部辐射力对动脉进行远程非侵入性施加。利用光学技术测量动脉的振动响应。识别出三种环形共振模式用于弹性模量的估计。可以获得动脉的粘弹性和复模量。在嵌入明胶的猪动脉上进行了实验。该估计仅需要动脉的直径，而不需要难以精确测量的动脉厚度。
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