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老年人长期住院的早期标志物:一项针对法国急症医院908名住院患者的前瞻性多中心研究。

Early markers of prolonged hospital stays in older people: a prospective, multicenter study of 908 inpatients in French acute hospitals.

作者信息

Lang Pierre-Olivier, Heitz Damien, Hédelin Guy, Dramé Moustapha, Jovenin Nicolas, Ankri Joël, Somme Dominique, Novella Jean-Luc, Gauvain Jean Bernard, Couturier Pascal, Voisin Thierry, De Wazière Benoît, Gonthier Régis, Jeandel Claude, Jolly Damien, Saint-Jean Olivier, Blanchard François

机构信息

Department of Internal Geriatric Medicine, Hôpital de la Robertsau, CHRU de Strasbourg, Strasbourg, France.

出版信息

J Am Geriatr Soc. 2006 Jul;54(7):1031-9. doi: 10.1111/j.1532-5415.2006.00767.x.

Abstract

OBJECTIVES

To identify early markers of prolonged hospital stays in older people in acute hospitals.

DESIGN

A prospective, multicenter study.

SETTING

Nine hospitals in France.

PARTICIPANTS

One thousand three hundred six patients aged 75 and older were hospitalized through an emergency department (Sujet Agé Fragile: Evaluation et suivi (SAFEs)--Frail Elderly Subjects: Evaluation and follow-up).

MEASUREMENTS

Data used in a logistic regression were obtained through a gerontological evaluation of inpatients, conducted in the first week of hospitalization. The center effect was considered in two models as a random and fixed effect. Two limits were used to define a prolonged hospital stay. The first was fixed at 30 days. The second was adjusted for Diagnosis Related Groups according to the French classification (f-DRG).

RESULTS

Nine hundred eight of the 1,306 hospital stays that made up the cohort were analyzed. Two centers (n=298) were excluded because of a large volume of missing f-DRGs. Two-thirds of subjects in the cohort analyzed were women (64%), with a mean age of 84. One hundred thirty-eight stays (15%) lasted more than 30 days; 46 (5%) were prolonged beyond the f-DRG-adjusted limit. No sociodemographic variables seemed to influence the length of stay, regardless of the limit used. For the 30-day limit, only cognitive impairment (odds ratio (OR)=2.2, 95% confidence interval (CI)=1.2-4.0) was identified as a marker for prolongation. f-DRG adjustment revealed other clinical markers. Walking difficulties (OR=2.6, 95% CI=1.2-16.7), fall risk (OR=2.5, 95% CI=1.7-5.3), cognitive impairment (OR=7.1, 95% CI=2.3-49.9), and malnutrition risk (OR=2.5, 95% CI=1.7-19.6) were found to be early markers for prolonged stays, although dependence level and its evolution, estimated using the Katz activity of daily living (ADL) index, were not identified as risk factors.

CONCLUSION

When the generally recognized parameters of frailty are taken into account, a set of simple items (walking difficulties, risk of fall, risk of malnutrition, and cognitive impairment) enables a predictive approach to the length of stay of elderly patients hospitalized under emergency circumstances. Katz ADLs were not among the early markers identified.

摘要

目的

确定急性医院中老年人住院时间延长的早期标志物。

设计

一项前瞻性多中心研究。

地点

法国的九家医院。

参与者

1306名75岁及以上的患者通过急诊科住院(脆弱老年受试者:评估与随访(SAFEs))。

测量

用于逻辑回归的数据通过住院第一周对住院患者进行的老年病学评估获得。在两个模型中,中心效应被视为随机效应和固定效应。使用两个界限来定义住院时间延长。第一个固定为30天。第二个根据法国分类法(f-DRG)针对诊断相关组进行了调整。

结果

对构成队列的1306次住院中的908次进行了分析。由于大量f-DRG缺失,排除了两个中心(n = 298)。队列分析中的三分之二受试者为女性(64%),平均年龄84岁。138次住院(15%)持续超过30天;46次(5%)超过了f-DRG调整后的界限。无论使用何种界限,似乎没有社会人口统计学变量会影响住院时间。对于30天的界限,仅认知障碍(比值比(OR)= 2.2,95%置信区间(CI)= 1.2 - 4.0)被确定为住院时间延长的标志物。f-DRG调整揭示了其他临床标志物。发现行走困难(OR = 2.6,95% CI = 1.2 - 16.7)、跌倒风险(OR = 2.5,95% CI = 1.7 - 5.3)、认知障碍(OR = 7.1,95% CI = 2.3 - 49.9)和营养不良风险(OR = 2.5,95% CI = 1.7 - 19.6)是住院时间延长的早期标志物,尽管使用Katz日常生活活动(ADL)指数评估的依赖程度及其变化未被确定为风险因素。

结论

当考虑到公认的衰弱参数时,一组简单项目(行走困难、跌倒风险、营养不良风险和认知障碍)能够对急诊情况下住院老年患者的住院时间进行预测。Katz ADL不在已确定的早期标志物之列。

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