von Ungern-Sternberg B S, Regli A, Frei F J, Hammer J, Schibler A, Erb T O
Division of Anaesthesia, University Children's Hospital, Basel, Switzerland.
Anaesthesia. 2006 Aug;61(8):758-63. doi: 10.1111/j.1365-2044.2006.04720.x.
Caudal block results in a motor blockade that can reduce abdominal wall tension. This could interact with the balance between chest wall and lung recoil pressure and tension of the diaphragm, which determines the static resting volume of the lung. On this rationale, we hypothesised that caudal block causes an increase in functional residual capacity and ventilation distribution in anaesthetised children. Fifty-two healthy children (15-30 kg, 3-8 years of age) undergoing elective surgery with general anaesthesia and caudal block were studied and randomly allocated to two groups: caudal block or control. Following induction of anaesthesia, the first measurement was obtained in the supine position (baseline). All children were then turned to the left lateral position and patients in the caudal block group received a caudal block with bupivacaine. No intervention took place in the control group. After 15 min in the supine position, the second assessment was performed. Functional residual capacity and parameters of ventilation distribution were calculated by a blinded reviewer. Functional residual capacity was similar at baseline in both groups. In the caudal block group, the capacity increased significantly (p < 0.0001) following caudal block, while in the control group, it remained unchanged. In both groups, parameters of ventilation distribution were consistent with the changes in functional residual capacity. Caudal block resulted in a significant increase in functional residual capacity and improvement in ventilation homogeneity in comparison with the control group. This indicates that caudal block might have a beneficial effect on gas exchange in anaesthetised, spontaneously breathing preschool-aged children with healthy lungs.
骶管阻滞会导致运动阻滞,从而降低腹壁张力。这可能会影响胸壁与肺回缩压力以及膈肌张力之间的平衡,而这种平衡决定了肺的静态静息容积。基于这一理论,我们推测骶管阻滞会使麻醉状态下儿童的功能残气量增加,通气分布得到改善。我们对52名接受全身麻醉和骶管阻滞的择期手术健康儿童(体重15 - 30千克,年龄3 - 8岁)进行了研究,并将他们随机分为两组:骶管阻滞组和对照组。麻醉诱导后,首先在仰卧位(基线)进行测量。然后所有儿童转为左侧卧位,骶管阻滞组的患儿接受布比卡因骶管阻滞。对照组不进行任何干预。在仰卧位15分钟后,进行第二次评估。由一位不知情的评估者计算功能残气量和通气分布参数。两组在基线时功能残气量相似。在骶管阻滞组,骶管阻滞后功能残气量显著增加(p < 0.0001),而在对照组,功能残气量保持不变。在两组中,通气分布参数与功能残气量的变化一致。与对照组相比,骶管阻滞导致功能残气量显著增加,通气均匀性改善。这表明骶管阻滞可能对肺部健康的麻醉状态下自主呼吸的学龄前儿童的气体交换有有益影响。