García-Pastor Cuauhtemoc, López-González Francisco, Revuelta Rogelio, Nathal Edgar
Division of Neurosurgery, National Institute of Neurology and Neurosurgery, "Manuel Velasco Suarez," Mexico City 14269, Mexico.
Surg Neurol. 2006 Aug;66(2):207-11; discussion 211. doi: 10.1016/j.surneu.2006.01.027.
Trigeminal neuralgia secondary to a posterior fossa AVM has been seldom reported in the literature. Most of the cases have been published on a case report basis, and there is not a general agreement about the best way of treatment.
In this work, we analyze our experience with 5 cases of TN secondary to a posterior fossa AVM, treated at the Division of Neurosurgery from the National Institute of Neurology and Neurosurgery, "Manuel Velasco Suarez," Mexico City, Mexico, from January 1985 to December 2004.
Trigeminal neuralgia associated with an AVM occurred in 1.3% of 375 brain AVMs and 9.8% of 37 posterior fossa AVMs. All had received drug therapy unsuccessfully, and 2 of them underwent a percutaneous thermocoagulation without solving the neuralgia. In 4 patients, a microvascular decompression was completed with excellent results.
Even when different ways of treatment have been reported, it seems that percutaneous procedures (glycerol injection, thermocoagulation, or microcompression of the gasserian ganglia) give variable clinical results. The reported experience and our own results support the microvascular decompression of the trigeminal nerve as the best treatment whenever the total excision of the AVM cannot be accomplished.
后颅窝动静脉畸形(AVM)继发三叉神经痛在文献中鲜有报道。大多数病例仅以个案报告形式发表,对于最佳治疗方式尚无普遍共识。
在本研究中,我们分析了1985年1月至2004年12月期间,墨西哥城墨西哥国立神经病学与神经外科学研究所“曼努埃尔·贝拉斯科·苏亚雷斯”神经外科治疗的5例后颅窝AVM继发三叉神经痛的经验。
375例脑AVM中,AVM相关的三叉神经痛发生率为1.3%;37例后颅窝AVM中,发生率为9.8%。所有患者药物治疗均无效,其中2例接受经皮热凝治疗后神经痛仍未缓解。4例患者接受微血管减压术,效果良好。
尽管已有多种治疗方法的报道,但经皮治疗(甘油注射、热凝或半月神经节微压迫)的临床效果似乎不一。已报道的经验及我们自己的结果均支持,在无法完全切除AVM时,三叉神经微血管减压术是最佳治疗方法。