Goto Noboru, Goto Jun
Department of Anatomy, Showa University School of Medicine, Shinagawa-ku, Tokyo, Japan.
Hum Cell. 2006 May;19(2):49-64. doi: 10.1111/j.1749-0774.2006.00013.x.
It is very important to evaluate and accurately understand the various conditions of the human nervous system. In this review article, we introduce several morphometric reports that are proven to be accurate from the view point of various errors (range of tissue shrinkage ratios, microscopic multiple counting, artifacts of microscopic structures, etc.). We review the following aspects of the selected reports: methodology, developmental research, neuronal differences, gender differences, aging process and miscellaneous (nerve fibers, unmyelinated fibers, in relation to neuropathology, clinical image-analysis and immunohistochemistry).
评估并准确理解人类神经系统的各种状况非常重要。在这篇综述文章中,我们介绍了几份形态测量报告,从各种误差(组织收缩率范围、显微镜下多次计数、微观结构伪像等)的角度来看,这些报告已被证明是准确的。我们回顾所选报告的以下几个方面:方法学、发育研究、神经元差异、性别差异、衰老过程以及其他方面(神经纤维、无髓纤维、与神经病理学、临床图像分析和免疫组织化学的关系)。