Diaz Francisco J, Fernandez Sein Alicia, Gotay Felicita
Pediatric Critical Care Section, University Pediatric Hospital, University of Puerto Rico, San Juan.
P R Health Sci J. 2006 Mar;25(1):17-22.
Asses if Abdominal Compartment Syndrome (ACS) increases the morbidity and mortality of the Pediatric Intensive Care Unit patients and if early recognition and intervention with decompressive therapy will alter outcome and decrease mortality.
Pediatric Intensive Care Unit of the University Pediatric Hospital-UPR.
All patients admitted to the PICU from July 1, 1999 to June 30, 2002 were enrolled in the study. Those having a distended and/or tense abdomen on physical examination were identified at risk for intra-abdominal hypertension (IAH). IAH was diagnosed if the intra-abdominal pressure (IAP) was above 10 mmHg and with ACS if the IAH was accompanied by: hemodynamic instability, oliguria or anuria, metabolic acidosis and respiratory deterioration.
1052 patients were admitted to PICU. Ten patients with evidence of ACS were identified with an incidence of 0.9%. Ages ranged from 6 weeks to 12.3 years. Peak intravesical pressure measurements ranged from 17 to 39 mmHg. Inspiratory pressure was raised from a mean of 21.2 to 32.0 cmH2O. The PCO2 increased from a mean of 35.1 to 63 torr and the pH decreased from a mean of 7.40 to 7.12. Overall mortality was 40% for this patient population.
The outcome of pediatric critical care patients depends on multiple variables. Now there is evidence that in a select group of patients IAH and ACS play a significant role in their morbidity and mortality. This makes it mandatory for clinicians taking care of this population to be increasingly aware of this condition.
评估腹腔间隔室综合征(ACS)是否会增加儿科重症监护病房患者的发病率和死亡率,以及早期识别并采用减压治疗进行干预是否会改变预后并降低死亡率。
波多黎各大学儿童医院儿科重症监护病房。
纳入了1999年7月1日至2002年6月30日期间入住儿科重症监护病房的所有患者。那些体格检查发现腹部膨隆和/或紧张的患者被确定为有腹腔内高压(IAH)风险。如果腹腔内压力(IAP)高于10 mmHg,则诊断为IAH;如果IAH伴有血流动力学不稳定、少尿或无尿、代谢性酸中毒和呼吸功能恶化,则诊断为ACS。
1052例患者入住儿科重症监护病房。确定了10例有ACS证据的患者,发病率为0.9%。年龄范围为6周至12.3岁。膀胱内压峰值测量值在17至39 mmHg之间。吸气压力从平均21.2 cmH₂O升至32.0 cmH₂O。二氧化碳分压从平均35.1 torr升至63 torr,pH值从平均7.40降至7.12。该患者群体的总体死亡率为40%。
儿科重症监护患者的预后取决于多个变量。现在有证据表明,在特定的一组患者中,IAH和ACS在其发病率和死亡率中起重要作用。这使得照顾这一群体的临床医生必须越来越意识到这种情况。