Monk Timothy H, Buysse Daniel J, Hall Martica, Nofzinger Eric A, Thompson Wesley K, Mazumdar Sati A, Reynolds Charles F
Clinical Neuroscience Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
Chronobiol Int. 2006;23(4):831-41. doi: 10.1080/07420520600827152.
Compared to younger adults, seniors (> or = 60 yrs) often adopt a highly regular lifestyle, perhaps as an adaptive response to age-related changes in their sleep and circadian rhythms. At baseline, diary measures of lifestyle regularity (SRM-5) were obtained from 104 seniors of three separate groups. Thirty-three subjects were challenged by spousal bereavement or the need to care for a spouse at home with dementia (Challenged); 33 were suffering from formally diagnosed (DSM-IV) insomnia (Insomnia); and 38 were healthy, well-functioning older seniors in the second half of their eighth decade of life or later (Healthy Older). The objective of this study was to determine whether lifestyle regularity increased as a function of age within each of these three senior groups. Overall, age was significantly correlated with SRM-5 (r=0.41, p<0.001), with the SRM score increasing by 0.67 units/decade. The same was true for the Challenged and Insomnia groups, which also showed a significant correlation between SRM and age (Challenged: r=0.48, p<0.01; Insomnia: r=0.36, p<0.05), though with a slightly faster rate of SRM increase in the Challenged (0.95 units/decade) than Insomnia (0.55 units/decade) group. Perhaps there was no correlation between age and SRM (r=0.07, n.s.) in the Healthy Older group due to the small age range, although this group did have a higher overall SRM score than the other two groups (p<0.01). The study thus confirmed that the previously observed increase in lifestyle regularity over the adult lifespan persists into later life. This may represent an adaptive behavioral response that might be used in future therapeutic approaches.
与年轻人相比,老年人(≥60岁)通常采用高度规律的生活方式,这可能是对与年龄相关的睡眠和昼夜节律变化的一种适应性反应。在基线时,从三个不同组别的104名老年人那里获取了生活方式规律性的日记测量值(SRM-5)。33名受试者受到配偶丧亡或在家照顾患有痴呆症配偶的需求的挑战(受挑战组);33名患有正式诊断(DSM-IV)的失眠症(失眠组);38名是健康、功能良好的八十多岁后半期及更年长的老年人(健康老年组)。本研究的目的是确定在这三个老年组中的每一组内,生活方式规律性是否随年龄增长而增加。总体而言,年龄与SRM-5显著相关(r = 0.41,p < 0.001),SRM得分每十年增加0.67个单位。受挑战组和失眠组也是如此,它们的SRM与年龄之间也显示出显著相关性(受挑战组:r = 0.48,p < 0.01;失眠组:r = 0.36,p < 0.05),不过受挑战组(0.95个单位/十年)的SRM增加速率略快于失眠组(0.55个单位/十年)。由于年龄范围较小,健康老年组中年龄与SRM之间可能没有相关性(r = 0.07,无统计学意义),尽管该组的总体SRM得分高于其他两组(p < 0.01)。该研究因此证实,先前观察到的成年期生活方式规律性的增加在晚年依然存在。这可能代表一种适应性行为反应,可用于未来的治疗方法中。