Guo Wei, Tang Shun, Dong Sen, Li Xiao
Musculoskeletal Tumor Center, People's Hospital, Peking University, Beijing 100044, China.
Zhonghua Wai Ke Za Zhi. 2006 Jun 15;44(12):813-6.
To discuss the resection of tumors, reconstruction of defects.
Sixty-one patients with tumors in ileum were treated surgically in People's Hospital from July 1998 to July 2004. The series comprised 38 males and 23 females with an average age of 43 years old (range from 12 to 78 years old). According to Enneking staging system, 36 cases had lesions in region I, 17 cases in region I and II, and 8 cases in region I and IV. After tumor resected, posterior fixation system of spine was applied to reconstruct the integrality of pelvic ring in series of region I cases. The four pedicle screws were implanted in the lumbar and sacrum superiorly, pubis and ischium inferiorly. For children patients, bone graft or bone cement and Steinmann's pins internal fixation was applied to reconstruct the pelvis.
Among all the 61 cases, 48 cases followed up from 16 months to 6 years. Thirty-three cases were survived and had no local recurrence or metastasis. Fifteen cases were dead. Oncology result: local recurrence were found in 19.4% patients with region I resection (7/36), the resection level was close to acetabulum (in order to reserve the acetabulum), and it might be the reason of recurrence. 35.3% of patients (6/17) with region I and II resection had local recurrence, the recurrence maybe related to residual tumor after curettage. 50.0% of the patients (4/8) with region I and IV resection had local recurrence, the tumor residual in sacrum might be the reason of recurrence. Functional result: all of the 36 cases received region I resection regained normal walking function. The hip joint function was normal in 17 cases received tumor curettage, bone cement or hip joint replacement.
The posterior fixation system of spine can be used to reconstruct the integrality of pelvic ring after resection of iliac tumors. Simple reconstruction is more favorable for child patients. Allograft or self-ileum can be implanted in the space of sacral wing and residual ileum, and the bone graft is fixed with compressional screw.
探讨肿瘤切除及缺损重建方法。
1998年7月至2004年7月,我院对61例回肠肿瘤患者实施手术治疗。其中男性38例,女性23例,平均年龄43岁(12~78岁)。按Enneking分期系统,Ⅰ区病变36例,Ⅰ、Ⅱ区病变17例,Ⅰ、Ⅳ区病变8例。Ⅰ区病例肿瘤切除后,应用脊柱后路内固定系统重建骨盆环完整性,于腰、骶部向上植入4枚椎弓根螺钉,耻骨、坐骨向下植入。儿童患者采用植骨或骨水泥加斯氏针内固定重建骨盆。
61例中,48例获16个月至6年随访。33例存活,无局部复发及远处转移;15例死亡。肿瘤学结果:Ⅰ区切除患者局部复发率19.4%(7/36),切除平面靠近髋臼(为保留髋臼),可能是复发原因;Ⅰ、Ⅱ区切除患者局部复发率35.3%(6/17),复发可能与刮除术后肿瘤残留有关;Ⅰ、Ⅳ区切除患者局部复发率50.0%(4/8),骶骨肿瘤残留可能是复发原因。功能结果:Ⅰ区切除的36例患者均恢复正常行走功能;17例肿瘤刮除、骨水泥填充或髋关节置换患者髋关节功能正常。
脊柱后路内固定系统可用于髂骨肿瘤切除后骨盆环完整性重建,儿童患者采用简单重建更有利。异体骨或自体回肠可植入骶骨翼及残留回肠间隙,并用加压螺钉固定植骨。