以视觉障碍为表现的散发性克雅氏病的MM2-皮质型

The MM2-cortical form of sporadic Creutzfeldt-Jakob disease presenting with visual disturbance.

作者信息

Nozaki I, Hamaguchi T, Noguchi-Shinohara M, Ono K, Shirasaki H, Komai K, Kitamoto T, Yamada M

机构信息

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan.

出版信息

Neurology. 2006 Aug 8;67(3):531-3. doi: 10.1212/01.wnl.0000228224.35678.60.

DOI:10.1212/01.wnl.0000228224.35678.60

PMID:16894125

Abstract

A subclass of sporadic Creutzfeldt-Jakob disease (sCJD) characterized by onset with visual symptoms (Heidenhain variant) has been reported to belong to the MM1 or MV1 type according to Parchi's classification. The authors report a 65-year-old woman with MM2-cortical sCJD with slowly progressive visual disturbance as the initial symptom. Diffusion-weighted MRIs revealed hyperintensity in both occipital cortices at an early stage.

摘要

据报道，散发性克雅氏病（sCJD）的一个以视觉症状起病（海德汉变型）的亚类，根据帕尔基分类属于MM1或MV1型。作者报告了一名65岁女性，患有MM2-皮质型sCJD，以缓慢进展的视觉障碍为初始症状。扩散加权磁共振成像显示早期双侧枕叶皮质高信号。