Ando Satoshi, Hattori Kazunori, Endo Tsuyoshi, Inai Hiromu, Matsueda Kiyoshi, Imazuru Tomohiro, Sakakibara Yuzuru, Kawai Koji, Shimazui Toru, Akaza Hideyuki
Department of Urology, Tsukuba Medical Center Hospital.
Nihon Hinyokika Gakkai Zasshi. 2006 Jul;97(5):752-6. doi: 10.5980/jpnjurol1989.97.752.
A 37-year-old man underwent Miles' operation and adjuvant irradiation therapy for rectum cancer in 1999. The patient suffered from bilateral ureteral stricture after the previous therapies. Bilateral double-J ureteral stents were inserted and exchanged at regular intervals. Four years after the start of ureteral stenting, he complicated with gross hematuria and dysuria. When the right double-J stent was exchanged, massive bleeding from external opening of urethra was observed. Retrograde pyelography showed right uretero-iliac arterial fistula. Since endovascular treatment with covered stents had failed, we performed right common iliac artery embolization and femoral-femoral artery bypass. Two days after the operation, gross hematuria developed again. When the left ureteral stent was exchanged, active bleeding from the external meatus of urethra was revealed. Angiography showed extravasation from left common iliac artery. We diagnosed left uretero-iliac arterial fistula. Although we tried endovascular treatment with covered stent that was made of artificial vessel graft and metallic stent, thromboembolism was occurred in the covered stent. Finally, right axillo-femoral artery bypass was indicated. The last treatment achieved long-term good control of uretero-arterial fistula. The present case shows that uretero-arterial fistula is a serious complication of long-term ureteral stenting, especially in the case of post pelvic surgery and irradiation.
一名37岁男性于1999年接受了直肠癌的腹会阴联合切除术及辅助放疗。患者在先前治疗后出现双侧输尿管狭窄。双侧均置入了双J型输尿管支架,并定期更换。输尿管支架置入开始4年后,他出现了肉眼血尿和排尿困难。更换右侧双J支架时,观察到尿道口大量出血。逆行肾盂造影显示右输尿管-髂动脉瘘。由于覆膜支架的血管内治疗失败,我们进行了右髂总动脉栓塞及股-股动脉搭桥术。术后两天,再次出现肉眼血尿。更换左侧输尿管支架时,发现尿道口有活动性出血。血管造影显示左髂总动脉有造影剂外渗。我们诊断为左输尿管-髂动脉瘘。尽管我们尝试使用由人工血管移植物和金属支架制成的覆膜支架进行血管内治疗,但覆膜支架内发生了血栓栓塞。最后,进行了右腋-股动脉搭桥术。最后一次治疗使输尿管-动脉瘘得到了长期良好的控制。本病例表明,输尿管-动脉瘘是长期输尿管支架置入的严重并发症,尤其是在盆腔手术后放疗的情况下。