Luo Lan, Pino Joseph
Department of Internal Medicine, Coastal AHEC, University of North Carolina School of Medicine, 2131 South 17th Street, Wilmington, NC 28409, USA.
Lung. 2006 May-Jun;184(3):187-93. doi: 10.1007/s00408-005-2579-7.
Spinal tuberculomas are extrapulmonary manifestations of tuberculosis involving the central nervous system. They are characterized as extradural, intradural extramedullary, or intradural, according to their location. Intradural extramedullary tuberculomas are extremely rare. There have been only 24 case reports found in English language literature. Our case is the only documented intradural extramedullary tuberculoma in a non-HIV-infected patient in North America. A literature review using a Medline search from 1966 to the present is performed to characterize the clinical spectrum of the three types of tuberculomas and review the diagnosis and management of this potentially curable disease. An analysis of the cases of intradural extramedullary tuberculomas published since 1984 is performed to highlight the unique characteristics of this rare disease.
脊柱结核瘤是结核病累及中枢神经系统的肺外表现。根据其位置,可分为硬膜外、硬膜内髓外或硬膜内结核瘤。硬膜内髓外结核瘤极为罕见。英文文献中仅发现24例病例报告。我们的病例是北美非HIV感染患者中唯一有记录的硬膜内髓外结核瘤。通过对1966年至今的医学文献数据库(Medline)进行检索,进行文献综述,以描述三种类型结核瘤的临床谱,并回顾这种潜在可治愈疾病的诊断和治疗。对1984年以来发表的硬膜内髓外结核瘤病例进行分析,以突出这种罕见疾病的独特特征。