Xu Pengjing, Lu Zhong-Lin, Qiu Zhuping, Zhou Yifeng
Vision Research Lab, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, PR China.
Vision Res. 2006 Oct;46(21):3748-60. doi: 10.1016/j.visres.2006.06.013. Epub 2006 Aug 14.
In this study, we applied the external noise method and the PTM model to identify mechanisms underlying performance deficits in amblyopia. Amblyopic and normal observers performed a Gabor orientation identification task in fovea. White external noise was added to the Gabor stimuli. Threshold versus external noise contrast (TvC) functions were measured at two performance criterion levels. For a subset of observers, we also manipulated the center spatial frequency of the Gabor. We found that two independent factors contributed to amblyopic deficits: (1) increased additive internal noise, and (2) deficient perceptual templates. Whereas increased additive noise underlay performance deficits in all spatial frequencies, the degree of perceptual template deterioration increased with the center spatial frequency of the Gabor.
在本研究中,我们应用外部噪声方法和PTM模型来确定弱视患者表现缺陷背后的机制。弱视观察者和正常观察者在中央凹执行了一项Gabor方向识别任务。向Gabor刺激添加了白色外部噪声。在两个表现标准水平上测量了阈值与外部噪声对比度(TvC)函数。对于一部分观察者,我们还操纵了Gabor的中心空间频率。我们发现有两个独立因素导致了弱视缺陷:(1)加性内部噪声增加,以及(2)感知模板缺陷。虽然加性噪声增加是所有空间频率下表现缺陷的基础,但感知模板退化的程度随着Gabor的中心空间频率增加而增加。