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光动力疗法成功治疗视网膜血管瘤样增殖。

Successful treatment of retinal angiomatous proliferation by photodynamic therapy.

作者信息

Gómez-Ulla Francisco, Abraldes Maximino J, Fernández Maribel, Olmedo María

机构信息

Universidad de Santiago de Compostela, Hospital Provincial de Conxo, Spain.

出版信息

Optom Vis Sci. 2006 Aug;83(8):546-9. doi: 10.1097/01.opx.0000230279.95171.71.

DOI:10.1097/01.opx.0000230279.95171.71
PMID:16909080
Abstract

PURPOSE

The purpose of this study is to describe a patient with retinal angiomatous proliferation (RAP) treated successfully by photodynamic therapy.

METHODS

A 74-year-old white woman was referred to our clinic for evaluation as a result of progressive decrease of vision in the right eye. Visual acuity was 20/100 in the affected right eye. The findings of fluorescein and indocyanine green angiography were consistent with a diagnosis of RAP, and cystoid macular edema was also revealed by optical coherence tomography (OCT). Photodynamic therapy (PDT) was carried out because of visual deterioration and localization of the RAP.

RESULTS

The RAP was treated with PDT, and an improvement in visual acuity to 20/60 was noted 4 months after treatment and 20/40 after 6 months. The resolution of the lesion was confirmed by fluorescein angiography, indocyanine green angiography, and OCT.

CONCLUSIONS

Photodynamic therapy can be effective for the treatment of RAP when it is associated with visual acuity decrease and is located near the fovea.

摘要

目的

本研究旨在描述一名通过光动力疗法成功治疗的视网膜血管瘤样增殖(RAP)患者。

方法

一名74岁白人女性因右眼视力逐渐下降被转诊至我院门诊进行评估。患侧右眼视力为20/100。荧光素和吲哚菁绿血管造影结果符合RAP诊断,光学相干断层扫描(OCT)也显示存在黄斑囊样水肿。由于视力恶化以及RAP的定位,遂进行了光动力疗法(PDT)。

结果

对RAP进行了PDT治疗,治疗后4个月视力提高到20/60,6个月后提高到20/40。荧光素血管造影、吲哚菁绿血管造影和OCT证实病变消退。

结论

当RAP与视力下降相关且位于黄斑中心凹附近时,光动力疗法对其治疗可能有效。

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