Yang Dae Hyeok, Ko Jong Tae, Kim Yong Sik, Kim Moon Suk, Shin Hyung Sik, Rhee John M, Khang Gilson, Lee Hai Bang
Department of Advanced Organic Materials Engineering, Chonbuk National University, 664-14, Dukjin-gu, Jeonju 561-756, South Korea.
J Biomater Sci Polym Ed. 2006;17(7):807-20. doi: 10.1163/156856206777656544.
In our previous study, we manufactured a reinforced poly(methylmethacrylate) (PMMA) bone cement with 3 wt% of the surface-modified ultra high molecular weight polyethylene (UHMWPE) powder to improve its poor mechanical and thermal properties resulting from unreacted methylmethacrylate (MMA), the generation of bubble and shrinkage, and high curing temperature. In the present study, the effect of ratios of MMA and N,N'-dimethyl-p-toluidine (DMPT) solutions in redox polymerization system was investigated for the surface modification of UHMWPE powder. We characterized physical and chemical properties of surface-modified UHMWPE powder and reinforced bone cements by a scanning electron microscope, ultimate tensile strength (UTS) and curing temperature (Tmax). It was found that UTSs (41.3-51.3 MPa) of the reinforced PMMA bone cements were similar to those (44.5 MPa) of conventional PMMA bone cement (control), as well as significantly higher (P < 0.05) than those (33.8 MPa) of 3 wt% unmodified UHMWPE powder-impregnated bone cement. In particular, the UTS of redox polymerization system using MMA/DMPT solution was better than that of radical system using MMA/xylene solution. Also, Tmax of the reinforced PMMA bone cements decreased from 103 to 72-84 degrees C. From these results, we confirmed that the surface-modified UHMWPE powder can be used as reinforcing agent to improve the mechanical and thermal properties of conventional PMMA bone cement.
在我们之前的研究中，我们制备了一种含有3 wt%表面改性超高分子量聚乙烯（UHMWPE）粉末的增强聚甲基丙烯酸甲酯（PMMA）骨水泥，以改善其因未反应的甲基丙烯酸甲酯（MMA）、气泡产生和收缩以及高固化温度而导致的较差的机械性能和热性能。在本研究中，研究了氧化还原聚合体系中MMA与N,N'-二甲基对甲苯胺（DMPT）溶液的比例对UHMWPE粉末表面改性的影响。我们通过扫描电子显微镜、极限拉伸强度（UTS）和固化温度（Tmax）对表面改性的UHMWPE粉末和增强骨水泥的物理和化学性质进行了表征。结果发现，增强PMMA骨水泥的UTS（41.3 - 51.3 MPa）与传统PMMA骨水泥（对照）的UTS（44.5 MPa）相似，并且显著高于（P < 0.05）3 wt%未改性UHMWPE粉末浸渍骨水泥的UTS（33.8 MPa）。特别是，使用MMA/DMPT溶液的氧化还原聚合体系的UTS优于使用MMA/二甲苯溶液的自由基体系。此外，增强PMMA骨水泥的Tmax从103℃降至72 - 84℃。从这些结果中我们证实，表面改性的UHMWPE粉末可以用作增强剂来改善传统PMMA骨水泥的机械性能和热性能。
