Lucena Rita de Cássia G, de Mello Roberto J V, Lessa José Ronaldo, Cavalcante George M, Ribeiro Marcelo
Departamento de Patologia, Universidade Federal de Pernambuco, Avenida Hélio Falcão 505/601, 51021-070 Recife PE, Brazil.
Arq Neuropsiquiatr. 2006 Jun;64(2B):441-5. doi: 10.1590/s0004-282x2006000300017.
Glioblastoma multiforme (GBM) is the glial tumor with the highest grade of malignity. It mainly affects the cerebral hemispheres, presenting general or focal signs and symptoms, which depend on the size, the location of the lesion and rate of growth of the tumor.
To analyze the relationship between motor impairment and GBM topography.
We studied 43 cases of GBM, related to the age, gender, localization and motor impairment.
The occurrence of the tumor was preponderant in adults (mean age 55 years old), men (55.82%), and frontal lobe (approximately 40%). The principal motor impairment was hemiparesis, with the exception of 2 cases in the frontal lobe, 2 temporal, 1 parietal, 1 occipital and 1 frontotemporal.
The clinical-topographic findings lead to consider the infiltrative effects (broad lesions) are responsible for the motor impairment rather than compressive effects (located lesions).
多形性胶质母细胞瘤（GBM）是恶性程度最高的胶质瘤。它主要影响大脑半球，表现出一般或局灶性体征和症状，这取决于肿瘤的大小、病变位置和生长速度。
分析运动障碍与GBM部位的关系。
我们研究了43例GBM病例，涉及年龄、性别、部位和运动障碍。
肿瘤的发生在成年人（平均年龄55岁）、男性（55.82%）和额叶（约40%）中占优势。主要运动障碍是偏瘫，额叶有2例、颞叶有2例、顶叶有1例、枕叶有1例以及额颞叶有1例除外。
临床部位学发现提示，浸润性效应（广泛病变）而非压迫性效应（局限性病变）是导致运动障碍的原因。
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