在做出决策时，髓系祖细胞渴望得到积极的反馈。
When it comes to decisions, myeloid progenitors crave positive feedback.
作者信息
Muzzey Dale, van Oudenaarden Alexander
机构信息
Department of Physics, Massachusetts Institute of Technology, Cambridge, 02139, USA.
出版信息
Cell. 2006 Aug 25;126(4):650-2. doi: 10.1016/j.cell.2006.08.007.
PMID:16923384
Abstract
Positive feedback is a ubiquitous feature of networks that establish and maintain cellular decisions. In this issue of Cell, Laslo et al. (2006) demonstrate how a feedback loop comprised of two mutual repressors regulates the differentiation of myeloid progenitors into either macrophages or neutrophils.
摘要
正反馈是建立和维持细胞决策的网络中普遍存在的一个特征。在本期《细胞》杂志中，拉兹洛等人（2006年）展示了一个由两个相互抑制因子组成的反馈回路如何调节髓系祖细胞向巨噬细胞或中性粒细胞的分化。
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