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良性疾病行保守性腮腺切除术后发生面瘫和严重味觉出汗综合征的风险:610例手术分析

Risk of facial palsy and severe Frey's syndrome after conservative parotidectomy for benign disease: analysis of 610 operations.

作者信息

Guntinas-Lichius Orlando, Gabriel Bettina, Klussmann J Peter

机构信息

Clinic of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Germany.

出版信息

Acta Otolaryngol. 2006 Oct;126(10):1104-9. doi: 10.1080/00016480600672618.

Abstract

CONCLUSIONS

Advanced age, long operation time and large specimen volume were significant risk factors for transient facial palsy after conservative parotidectomy. Revision operation was the only risk factor for development of a permanent palsy. Risk factors for Frey's syndrome were not found. The incidence of Frey's syndrome was not altered by the use of a sternocleidomastoid muscle flap or other implantation material.

OBJECTIVES

The results of studies identifying risk factors for facial palsy and Frey's syndrome after parotidectomy are contradictory. This study attempted to identify these risk factors by performing a retrospective review of a large series of patients.

PATIENTS AND METHODS

A total of 610 standardized conservative parotidectomies for benign diseases performed between 1989 and 2004 were studied retrospectively. The risk factors for facial palsy and Frey's syndrome were determined by univariate and if possible by multivariate analysis of variables related to patient demographics and operation characteristics.

RESULTS

The rates of transient facial palsies, permanent facial palsies and Frey's syndrome were 18%, 4%, and 4%, respectively. Significant univariate and multivariate risk factors for development of a transient facial palsy were age>70 years, operation time>260 min, and a specimen volume>70 cm3. The only significant risk factor for the development of a permanent palsy was prior surgery. A significant risk factor for the development of Frey's syndrome could not be estimated.

摘要

结论

高龄、手术时间长和标本体积大是保守性腮腺切除术后发生暂时性面瘫的重要危险因素。再次手术是发生永久性面瘫的唯一危险因素。未发现味觉出汗综合征的危险因素。使用胸锁乳突肌瓣或其他植入材料并未改变味觉出汗综合征的发生率。

目的

关于腮腺切除术后面瘫和味觉出汗综合征危险因素的研究结果相互矛盾。本研究试图通过对大量患者进行回顾性分析来确定这些危险因素。

患者与方法

回顾性研究了1989年至2004年间共610例因良性疾病行标准化保守性腮腺切除术的患者。通过对与患者人口统计学和手术特征相关的变量进行单因素分析,如有可能进行多因素分析,来确定面瘫和味觉出汗综合征的危险因素。

结果

暂时性面瘫、永久性面瘫和味觉出汗综合征的发生率分别为18%、4%和4%。发生暂时性面瘫的显著单因素和多因素危险因素为年龄>70岁、手术时间>260分钟和标本体积>70 cm³。发生永久性面瘫的唯一显著危险因素是既往手术。无法评估味觉出汗综合征发生的显著危险因素。

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