微生物产生的羟基柠檬酸的绝对构型。

Absolute configuration of hydroxycitric acid produced by microorganisms.

作者信息

Hida Hiroyuki, Yamada Takashi, Yamada Yasuhiro

机构信息

Department of Applied Biological Science, Faculty of Life Science and Biotechnology, Fukuyama University, Hiroshima, Japan.

出版信息

Biosci Biotechnol Biochem. 2006 Aug;70(8):1972-4. doi: 10.1271/bbb.50701.

DOI:10.1271/bbb.50701

PMID:16926511

Abstract

Optical resolution for (2S,3R) and (2R,3S)-hydroxycitric acid (HCA) enantiomers was developed using chiral column chromatography. HCA from Bacillus megaterium G45C and Streptomyces sp. U121, newly isolated in our previous study, was analyzed to determine the absolute configuration. These results indicate that both strains generate optically pure (2S,3R)-hibiscus type HCA enantiomer.

摘要

使用手性柱色谱法对（2S，3R）和（2R，3S）-羟基柠檬酸（HCA）对映体进行了光学拆分。对我们之前研究中新分离出的巨大芽孢杆菌G45C和链霉菌属U121中的HCA进行分析，以确定其绝对构型。这些结果表明，这两种菌株均产生光学纯的（2S，3R）-木槿型HCA对映体。