Iacoboni Marco
Ahmanson-Lovelace Brain Mapping Center, Department of Psychiatry and Biobehavioral Sciences, NeuroPsychiatric Institute, Brain Research Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Trends Cogn Sci. 2006 Oct;10(10):431-3. doi: 10.1016/j.tics.2006.08.002. Epub 2006 Aug 23.
A new brain imaging study demonstrates that patients with autism have a strikingly different pattern of brain activity compared with control subjects. During cognitive tasks, cortical areas known as the "default state" network--areas that have been implicated in both self-referential processing and processing of socially relevant information--typically reduce their brain activity. In patients with autism, such a reduction was not observed. This new finding indicates that a core deficit in autism might be related to the construal of a sense of self in its relationship with others and will certainly generate exciting new research on the neurobiology of autism.
一项新的脑成像研究表明,与对照组相比,自闭症患者的大脑活动模式显著不同。在认知任务期间,被称为“默认状态”网络的皮质区域——这些区域与自我参照处理和社会相关信息处理都有关联——通常会减少其大脑活动。在自闭症患者中,并未观察到这种减少。这一新发现表明,自闭症的一个核心缺陷可能与自我与他人关系中的自我意识构建有关,并且肯定会引发关于自闭症神经生物学的令人兴奋的新研究。