Bahíllo Curieses Maria P, Hermoso López F, García Fernández J A, Ochoa Sangrador C, Rodrigo Palacios J, de la Torre Santos S I, Marugán de Miguelsanz J M, Manzano Recio F, García Velázquez J, Lema Garret T J
Hospital Clínico Universitario de Valladolid, Spaña.
An Pediatr (Barc). 2006 Jul;65(1):15-21. doi: 10.1157/13090893.
The incidence of type 1 diabetes shows wide geographical variability and heterogeneity. The aim of this study was to determine the incidence and prevalence of type 1 diabetes in children and adolescents ages less than 15 years in the different provinces of Castilla-León.
To determine incidence, all new cases of type 1 diabetes with onset under 15 years of age in 2003-2004 were obtained. Incidence was expressed as the crude value with the corresponding confidence interval and as standardized incidence. The capture-recapture method was used to calculate the completeness of ascertainment. To determine prevalence, all cases of type 1 diabetes in persons ages less than 15 years at 31 December 2004 were obtained.
Incidence showed wide variability among the different provinces of Castilla-León. The highest values were found in Segovia (38.77/100,000/year), Valladolid (32.07/100,000/ year) and Avila (23.21/100,000/year) and the lowest in Zamora (8.14/100,000/year). Incidences were highest in the 5-9 years age group in all provinces except Burgos. Prevalence was highest in Segovia (1.54/1,000), Valladolid (1.41/1,000), Avila (1.38/1,000) and Zamora (1.32/1,000) and lowest in Burgos (0.91/1,000).
Castilla-León seems to have one of the highest incidences of type 1 diabetes in Spain; several of its provinces have values similar to those in Northern Europe.
1型糖尿病的发病率在地域上呈现出广泛的变异性和异质性。本研究的目的是确定卡斯蒂利亚-莱昂不同省份15岁以下儿童和青少年1型糖尿病的发病率和患病率。
为确定发病率,获取了2003 - 2004年所有15岁以下发病的1型糖尿病新病例。发病率以粗值及其相应的置信区间表示,并作为标准化发病率。采用捕获-再捕获法计算确诊的完整性。为确定患病率,获取了2004年12月31日时15岁以下人群中所有1型糖尿病病例。
卡斯蒂利亚-莱昂不同省份的发病率差异很大。最高值出现在塞哥维亚(38.77/100,000/年)、巴利亚多利德(32.07/100,000/年)和阿维拉(23.21/100,000/年),最低值出现在萨莫拉(8.14/100,000/年)。除布尔戈斯外,所有省份5 - 9岁年龄组的发病率最高。患病率最高的是塞哥维亚(1.54/1,000)、巴利亚多利德(1.41/1,000)、阿维拉(1.38/1,000)和萨莫拉(1.32/1,000),最低的是布尔戈斯(0.91/1,000)。
卡斯蒂利亚-莱昂似乎是西班牙1型糖尿病发病率最高的地区之一;其几个省份的值与北欧相似。