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舌骨上入路治疗舌根鳞状细胞癌。

Suprahyoid approach to base-of-tongue squamous cell carcinoma.

作者信息

Mulwafu W, Fagan J J, Lentin R

机构信息

Division of Otolaryngology, University of Cape Town.

出版信息

S Afr J Surg. 2006 Aug;44(3):120, 122-4.

Abstract

OBJECTIVE

To evaluate the suprahyoid approach to treatment of squamous cell carcinoma of the base of the tongue at Groote Schuur Hospital between 1999 and 2004.

DESIGN AND METHOD

Retrospective analysis was done of patients with base-of-tongue squamous cell carcinoma treated using the suprahyoid approach.

RESULTS

Seventeen patients underwent treatment for base-of-tongue squamous cell carcinoma utilising the suprahyoid approach. Complete medical records were available for 15 of these patients. The most common presenting symptoms were neck mass (40%) and referred otalgia (33%). Alcohol was a risk factor in more patients (64%) than smoking (47%). Adverse pathological findings were present in less than 50% of patients (involved margins 20%, perineural invasion 40%, vascular invasion 33%). Functional outcome in terms of speech intelligibility was excellent and there were minimal swallowing problems, with most patients using compensatory strategies and dietary modification. There were 2 subsequent deaths (13%) as a result of distant metastasis and a second primary.

CONCLUSION

The suprahyoid approach to treatment of base-of-tongue squamous cell carcinoma provides good exposure, local tumour control and excellent functional outcome.

摘要

目的

评估1999年至2004年间在格罗特·舒尔医院采用舌骨上入路治疗舌根鳞状细胞癌的效果。

设计与方法

对采用舌骨上入路治疗的舌根鳞状细胞癌患者进行回顾性分析。

结果

17例患者采用舌骨上入路治疗舌根鳞状细胞癌。其中15例患者有完整的病历记录。最常见的症状是颈部肿块(40%)和牵涉性耳痛(33%)。饮酒作为危险因素的患者(64%)多于吸烟患者(47%)。不到50%的患者有不良病理表现(切缘受累20%,神经周围侵犯40%,血管侵犯33%)。语音清晰度方面的功能结果良好,吞咽问题极少,大多数患者采用代偿策略和饮食调整。因远处转移和第二原发肿瘤导致2例患者随后死亡(13%)。

结论

舌骨上入路治疗舌根鳞状细胞癌可提供良好的暴露、局部肿瘤控制和出色的功能结果。

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