Weinert Craig, Meller William
Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Psychosomatics. 2006 Sep-Oct;47(5):399-407. doi: 10.1176/appi.psy.47.5.399.
The authors enrolled 277 subjects with acute respiratory failure to describe the epidemiology of depressive disorders and antidepressant use during and after intensive care. By SCID criteria, the prevalence of major depressive episode at 2 months was 16%, and 16% had depressive disorder not otherwise specified. Mood disorder incidence was 25% or 28%, depending on methodology. Pre-ICU physical functioning and depression were associated with 2- and 6-month depression severity. At 2 months, the prevalence of antidepressant medication use was 49%, and the incidence was 28%. Depression and antidepressant pharmacotherapy are frequent during recovery from acute respiratory failure.
作者纳入了277例急性呼吸衰竭患者，以描述重症监护期间及之后抑郁症和抗抑郁药使用的流行病学情况。根据精神障碍诊断与统计手册标准，2个月时重度抑郁发作的患病率为16%，另有16%患有未另行说明的抑郁症。根据方法不同，情绪障碍的发病率为25%或28%。重症监护病房前的身体功能和抑郁与2个月及6个月时的抑郁严重程度相关。2个月时，抗抑郁药物的使用率为49%，发病率为28%。急性呼吸衰竭恢复期间，抑郁和抗抑郁药物治疗很常见。
