Lametschwandtner A, Staindl O
Zoologisches Institut, Universität Salzburg.
HNO. 1990 Jun;38(6):202-7.
Three keloids harvested during surgery were prepared for histology and scanning electron microscopy (SEM) of vascular corrosion casts. One well-filled keloid (12 cm x 7 cm) was examined by SEM. This specimen revealed a conspicuous increase in subepidermal venous vessels as well as prominent luminal bulging of the endothelial lining in arterial and venous vessels, shown by prominent surface imprint patterns on cast vessels. There were no tapered or compressed vessels. Blind ending vessels identified by cast morphology as vascular sprouts indicated keloid angiogenesis. The increase in (venous) vessels correlated very closely with the hyperaemic state of the keloid.
手术中获取的三个瘢痕疙瘩被制备用于组织学检查和血管铸型扫描电子显微镜(SEM)观察。对一个填充良好的瘢痕疙瘩(12厘米×7厘米)进行了SEM检查。该标本显示,表皮下静脉血管显著增多,动脉和静脉血管的内皮衬里出现明显的管腔膨出,铸型血管上有明显的表面印记图案。没有血管变细或受压的情况。通过铸型形态学鉴定为血管芽的盲端血管表明瘢痕疙瘩存在血管生成。(静脉)血管的增多与瘢痕疙瘩的充血状态密切相关。