Hyman Paul E
Department of Pediatrics, University of Kansas School of Medicine, 3901 Rainbow Boulevard, Mail stop 4004, Kansas City, KS 66160, USA.
Curr Gastroenterol Rep. 2006 Oct;8(5):425-9. doi: 10.1007/s11894-006-0029-1.
A majority of children and adolescents who have successful surgery to resect colon affected by Hirschsprung's disease suffer from digestive disorders, defecation problems, or both into adult life. In those with persistent symptoms following Hirschsprung's surgery, colon manometry facilitates a physiologic explanation for symptoms and guides treatment. Only a few patients born with Hirschsprung's disease make it to adult age before diagnosis and surgery, but their management does not differ from that of children with Hirschsprung's disease. The quality of life for patients with Hirschsprung's disease depends on psychosocial factors and not on childhood suffering or chronic symptoms.
大多数接受成功手术切除受先天性巨结肠症影响的结肠的儿童和青少年，在成年后会患有消化系统疾病、排便问题或两者皆有。在先天性巨结肠症手术后仍有持续症状的患者中，结肠测压有助于从生理学角度解释症状并指导治疗。只有少数患有先天性巨结肠症的患者在诊断和手术前活到成年，但他们的治疗与先天性巨结肠症儿童并无不同。先天性巨结肠症患者的生活质量取决于心理社会因素，而非童年时期的痛苦或慢性症状。
