Zhan Qing, Meng Ru
Department of Neuropathy, Tongji Hospital Affiliated to Tongji University, Shanghai 200065.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Aug;26(8):743-5.
The pathological changes of systemic lupus erythematosus (SLE) could involve multiple organs and systems, showing a complicated and multivariate clinical features. Since the authors held that the previous clinical disease-syndrome integrative thought can not embody the regularity in the diagnosis and treatment of SLE, in order to establish a novel operable thought of syndrome differentiation which could reflect the clinical practice of SLE, they suggested, in accordance with their clinical experience, that the basis for integration of the disease and its syndromes should not be SLE itself but the clinical manifestations of the organs and systems, such as fever, nervous system injury, lupus kidney, thrombocytopenic purpura of SLE, etc. They claimed that the new clinical thought of diagnosis and treatment will contribute to conduct systematic and standard research on SLE, and the regulation of TCM therapy based on syndrome differentiation would be more closer to the clinical practice of SLE.
系统性红斑狼疮(SLE)的病理变化可累及多个器官和系统,呈现出复杂多样的临床特征。由于作者认为既往的临床病证结合思路无法体现SLE诊疗的规律性,为建立一种能反映SLE临床实际、新颖且可操作的辨证思路,他们根据临床经验提出,病证结合的基础不应是SLE本身,而应是器官和系统的临床表现,如发热、神经系统损伤、狼疮性肾炎、SLE血小板减少性紫癜等。他们声称,这种新的临床诊疗思路将有助于对SLE进行系统规范的研究,且基于辨证的中医治疗规范化将更贴近SLE的临床实际。