Altaee Iqdam K, Jaleel Nedham A, Aljubury Harith M, Alshamaa Ihsan A, Gazala Shawqi
Department of Urology and Kidney Transplantation, Al-Karama Teaching Hospital - Kidney Transplantation Center, Baghdad, Iraq.
Saudi J Kidney Dis Transpl. 2006 Sep;17(3):408-14.
We retrospectively reviewed the records of 273 renal transplant recipients who received allograft transplants between 1994 and 2004 and recorded the incidence and types of de novo malignancies that developed in these patients. The study was carried out at the Al-karama and Al-rasheed kidney transplant centers in Baghdad, Iraq. A total of 16 patients developed malignancies. The tumors included Kaposi's sarcoma (KS) in eight patients, squamous cell carcinoma (SCC) in four, basal cell carcinoma (BCC) in two and both renal cell carcinoma of the allograft and brain tumor in one patient. Thus, KS was the most common malignancy encountered in our series, with a prevalence of 2.9%, followed by SCC observed in 1.5% and BCC found in 0.7% of the patients. The average latency period between transplantation and development of malignancy was 6.5 months for KS, 3.0 months for SCC and 8.5 months for BCC. To our knowledge, this is the first long-term follow-up study for malignant complications identified in kidney recipients in Iraq.
我们回顾性分析了1994年至2004年间接受同种异体移植的273例肾移植受者的记录,并记录了这些患者新发恶性肿瘤的发生率和类型。该研究在伊拉克巴格达的卡拉马和拉希德肾移植中心进行。共有16例患者发生了恶性肿瘤。肿瘤包括8例卡波西肉瘤(KS)、4例鳞状细胞癌(SCC)、2例基底细胞癌(BCC),还有1例患者同时发生了移植肾的肾细胞癌和脑肿瘤。因此,KS是我们研究系列中最常见的恶性肿瘤,患病率为2.9%,其次是SCC,在1.5%的患者中观察到,BCC在0.7%的患者中发现。移植与恶性肿瘤发生之间的平均潜伏期,KS为6.5个月,SCC为3.0个月,BCC为8.5个月。据我们所知,这是伊拉克肾移植受者恶性并发症的首次长期随访研究。