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辅助动静脉瘘作为挽救下肢静脉旁路移植且流出道不佳的一种手段。

Adjuvant arteriovenous fistula as means of rescue for infrapopliteal venous bypass with poor runoff.

作者信息

Laurila Katariina, Luther Michael, Roth Wolf-Dieter, Vilkko Pekka, Kantonen Ilkka, Teittinen Kari, Sihvo Eero I, Ihlberg Leo, Albäck Anders, Lepäntalo Mauri

机构信息

Department of Vascular Surgery, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

J Vasc Surg. 2006 Nov;44(5):985-91; discussion 992. doi: 10.1016/j.jvs.2006.06.037. Epub 2006 Sep 18.

Abstract

OBJECTIVE

The aim of this study was to assess the outcome of infrapopliteal bypass when an adjuvant arteriovenous (AV) fistula was reconstructed as means of rescue as a result of poor runoff. The design was a retrospective multicenter case-control study.

METHODS

Seventy-seven infrapopliteal vein bypasses required an adjuvant AV fistula among 1813 patients operated on for critical leg ischemia in 3 vascular centers between 1996 and 2003. The mean age was 74 years (range, 39-90 years). A total of 70% of the patients had diabetes, and 24% had undergone previous vascular surgery. In 25% of the bypasses, the distal anastomosis was in a crural artery, in 55% it was in the dorsal pedal artery, and in 20% it was in a plantar artery. An adjuvant AV fistula was reconstructed in all cases because of poor intraoperative arterial status, intraoperative angiography, or low intraoperative flow. A control group was retrieved that matched the study group according to the recipient artery and runoff score.

RESULTS

The primary and secondary patency were 61% and 75%, respectively, at 1 year in the AV fistula group and 57% and 71% in the control group. The 3-year patency rates were 49% and 62% for the AV fistula group and 46% and 71% for the control group, respectively. There was a 76% leg-salvage rate at 3 years in the study group, compared with 87% in the control group. There were no major complications related to the AV fistula. Intraoperative flow was increased from a median of 20 mL/min to 115 mL/min by the AV fistula (P = .003). The graft flow was significantly higher in the AV fistula group than in the control group (P = .001).

CONCLUSIONS

The adjuvant AV fistula increased graft flow significantly in a poor-outflow venous bypass. In this extreme patient group, acceptable patency and leg salvage was achieved without adverse effects. Despite this, the AV fistula did not improve the outcome.

摘要

目的

本研究旨在评估当因流出道不佳而将辅助性动静脉(AV)瘘作为补救手段重建时,腘下旁路手术的结果。研究设计为回顾性多中心病例对照研究。

方法

1996年至2003年期间,在3个血管中心为1813例严重下肢缺血患者实施手术,其中77例腘下静脉旁路手术需要辅助性AV瘘。平均年龄为74岁(范围39 - 90岁)。共有70%的患者患有糖尿病,24%的患者曾接受过血管手术。在25%的旁路手术中,远端吻合口位于小腿动脉,55%位于足背动脉,20%位于足底动脉。由于术中动脉状况不佳、术中血管造影或术中血流低,所有病例均重建了辅助性AV瘘。根据受体动脉和流出道评分选取了与研究组匹配的对照组。

结果

AV瘘组1年时的初级通畅率和次级通畅率分别为61%和75%,对照组分别为57%和71%。AV瘘组3年通畅率分别为49%和62%,对照组分别为46%和71%。研究组3年时的保肢率为76%,对照组为87%。未发生与AV瘘相关的重大并发症。AV瘘使术中血流从中位数20 mL/min增加到115 mL/min(P = .003)。AV瘘组的移植物血流明显高于对照组(P = .001)。

结论

辅助性AV瘘在流出道不佳的静脉旁路手术中显著增加了移植物血流。在这个极端患者群体中,实现了可接受的通畅率和保肢效果且无不良影响。尽管如此,AV瘘并未改善手术结果。

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