Laurila Katariina, Luther Michael, Roth Wolf-Dieter, Vilkko Pekka, Kantonen Ilkka, Teittinen Kari, Sihvo Eero I, Ihlberg Leo, Albäck Anders, Lepäntalo Mauri
Department of Vascular Surgery, Helsinki University Central Hospital, Helsinki, Finland.
J Vasc Surg. 2006 Nov;44(5):985-91; discussion 992. doi: 10.1016/j.jvs.2006.06.037. Epub 2006 Sep 18.
The aim of this study was to assess the outcome of infrapopliteal bypass when an adjuvant arteriovenous (AV) fistula was reconstructed as means of rescue as a result of poor runoff. The design was a retrospective multicenter case-control study.
Seventy-seven infrapopliteal vein bypasses required an adjuvant AV fistula among 1813 patients operated on for critical leg ischemia in 3 vascular centers between 1996 and 2003. The mean age was 74 years (range, 39-90 years). A total of 70% of the patients had diabetes, and 24% had undergone previous vascular surgery. In 25% of the bypasses, the distal anastomosis was in a crural artery, in 55% it was in the dorsal pedal artery, and in 20% it was in a plantar artery. An adjuvant AV fistula was reconstructed in all cases because of poor intraoperative arterial status, intraoperative angiography, or low intraoperative flow. A control group was retrieved that matched the study group according to the recipient artery and runoff score.
The primary and secondary patency were 61% and 75%, respectively, at 1 year in the AV fistula group and 57% and 71% in the control group. The 3-year patency rates were 49% and 62% for the AV fistula group and 46% and 71% for the control group, respectively. There was a 76% leg-salvage rate at 3 years in the study group, compared with 87% in the control group. There were no major complications related to the AV fistula. Intraoperative flow was increased from a median of 20 mL/min to 115 mL/min by the AV fistula (P = .003). The graft flow was significantly higher in the AV fistula group than in the control group (P = .001).
The adjuvant AV fistula increased graft flow significantly in a poor-outflow venous bypass. In this extreme patient group, acceptable patency and leg salvage was achieved without adverse effects. Despite this, the AV fistula did not improve the outcome.
本研究旨在评估当因流出道不佳而将辅助性动静脉(AV)瘘作为补救手段重建时,腘下旁路手术的结果。研究设计为回顾性多中心病例对照研究。
1996年至2003年期间,在3个血管中心为1813例严重下肢缺血患者实施手术,其中77例腘下静脉旁路手术需要辅助性AV瘘。平均年龄为74岁(范围39 - 90岁)。共有70%的患者患有糖尿病,24%的患者曾接受过血管手术。在25%的旁路手术中,远端吻合口位于小腿动脉,55%位于足背动脉,20%位于足底动脉。由于术中动脉状况不佳、术中血管造影或术中血流低,所有病例均重建了辅助性AV瘘。根据受体动脉和流出道评分选取了与研究组匹配的对照组。
AV瘘组1年时的初级通畅率和次级通畅率分别为61%和75%,对照组分别为57%和71%。AV瘘组3年通畅率分别为49%和62%,对照组分别为46%和71%。研究组3年时的保肢率为76%,对照组为87%。未发生与AV瘘相关的重大并发症。AV瘘使术中血流从中位数20 mL/min增加到115 mL/min(P = .003)。AV瘘组的移植物血流明显高于对照组(P = .001)。
辅助性AV瘘在流出道不佳的静脉旁路手术中显著增加了移植物血流。在这个极端患者群体中,实现了可接受的通畅率和保肢效果且无不良影响。尽管如此,AV瘘并未改善手术结果。