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使用骨颗粒和钛网对唇腭裂患者进行牙槽骨移植:一项定量研究。

Alveolar bone graft for patients with cleft lip/palate using bone particles and titanium mesh: A quantitative study.

作者信息

Matsui Yoshiro, Ohta Mizuho, Ohno Kohsuke, Nagumo Masao

机构信息

Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan.

出版信息

J Oral Maxillofac Surg. 2006 Oct;64(10):1540-5. doi: 10.1016/j.joms.2005.12.030.

Abstract

PURPOSE

This study evaluated the bone volume, height, and width that can be obtained in alveolar ridge augmentation using titanium mesh and autogenous bone particles in patients with cleft lip/palate.

PATIENTS AND METHODS

Subjects were 15 patients with cleft lip/palate requiring tertiary bone graft for implant therapy. Computed tomography (CT) scans were taken before removing the mesh, from 1 to 21 months after bone grafting. Forty-three reconstructed images corresponding to the positions for implant placement were selected for this study. The percent defect filled with bone (%BONE), defined as the percentage of newly formed bone in the space created by the mesh, was measured for image analyses. In linear analyses, 4 parameters were used: increased bone height (IBH), percent increased bone height (%IBH), increased bone width (IBW), and percent increased bone width (%IBW). Factors influencing the quantitative data and the clinical courses of placed implants were also explored.

RESULTS

The average %BONE was 91.1%. IBH averaged 4.4 mm, whereas %IBH averaged 88.5%. IBW averaged 4.6 mm, whereas %IBW averaged 86.4%. Little correlation was present between the quantitative data and patient age, or time interval. A significant correlation was identified between the data for span of the grafted area and %BONE (correlation coefficient value = -0.36). However, the diminishing rate was very low. No implants were lost postoperatively.

CONCLUSIONS

Alveolar ridge augmentation with titanium mesh and autogenous bone particles from the anterior iliac crest has very high predictability as a preimplant procedure in patients with cleft lip/palate.

摘要

目的

本研究评估了唇腭裂患者使用钛网和自体骨颗粒进行牙槽嵴增高术时可获得的骨体积、高度和宽度。

患者与方法

研究对象为15例需要进行三次骨移植以接受种植治疗的唇腭裂患者。在移除钛网前以及骨移植后1至21个月进行计算机断层扫描(CT)。本研究选取了43张对应种植体植入位置的重建图像。通过图像分析测量骨填充缺损百分比(%BONE),其定义为钛网所形成空间中新形成骨的百分比。在线性分析中,使用了4个参数:骨高度增加量(IBH)、骨高度增加百分比(%IBH)、骨宽度增加量(IBW)和骨宽度增加百分比(%IBW)。还探讨了影响定量数据和所植入种植体临床过程的因素。

结果

平均%BONE为91.1%。IBH平均为4.4毫米,而%IBH平均为88.5%。IBW平均为4.6毫米,而%IBW平均为86.4%。定量数据与患者年龄或时间间隔之间几乎没有相关性。在移植区域跨度数据与%BONE之间发现了显著相关性(相关系数值 = -0.36)。然而,减少率非常低。术后无种植体丢失。

结论

对于唇腭裂患者,使用钛网和来自髂前嵴的自体骨颗粒进行牙槽嵴增高术作为种植前手术具有很高的可预测性。

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