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骨锚定男性吊带与胶原蛋白植入物治疗男性尿失禁的比较。

Comparison of bone-anchored male sling and collagen implant for the treatment of male incontinence.

作者信息

Onur Rahmi, Singla Ajay

机构信息

Department of Urology, Firat University, Faculty of Medicine, Elazig, Turkey.

出版信息

Int J Urol. 2006 Sep;13(9):1207-11. doi: 10.1111/j.1442-2042.2006.01531.x.

Abstract

AIM

To compare the effectiveness of transurethral collagen injection and perineal bone-anchored male sling for the treatment of male stress urinary incontinence (SUI).

METHODS

Seventy-one men with SUI underwent either transurethral collagen injections (n = 34) or perineal bone-anchored male sling (n = 37) between June 1999 and October 2003. Most of the patients in each group had radical retropubic prostatectomy and/or external beam radiation therapy (EBRT) in relation to the cause of incontinence. There was one patient in both groups who only had EBRT for the cause. The mean duration of incontinence were 4.2 and 4.4 years, respectively. Collagen injections were carried out transurethrally either under regional or general anesthesia until co-aptation of mucosa was observed. The male sling was placed under spinal anesthesia with a bone drill using either absorbable or synthetic materials. Retrospectively, all patients were assessed for continence status and procedure-related morbidity, if present. The outcome of both procedures was also compared with the degree of incontinence.

RESULTS

Ten (30%) patients in the collagen group showed either significant improvement or were cured following injections. Preoperatively, the mean pad use in collagen group was 4.5 (SD 2.8) per day, whereas it was 2.2 (SD 1.1) after the injection(s). Collagen injection failed in 24 (70%) of the patients. Patients who received the male sling had a mean preoperative pad use of 3.7 (SD 1.5) and postoperatively, the number decreased to 1.6 (SD 1.2). Most of the patients in this group were either totally dry or significantly improved (n: 28, 76%). There was a statistically significant difference between two groups in respect to success rate (P < 0.05). Analysis of treatment outcome with the degree of incontinence revealed that the male sling is most effective in patients with minimal-to-moderate incontinence.

CONCLUSIONS

Our results suggest that the male sling, a minimally invasive procedure, is more effective than collagen implant in the treatment of mild-to-moderate SUI in men.

摘要

目的

比较经尿道胶原蛋白注射和会阴骨锚定男性吊带治疗男性压力性尿失禁(SUI)的有效性。

方法

1999年6月至2003年10月期间,71例SUI男性患者接受了经尿道胶原蛋白注射(n = 34)或会阴骨锚定男性吊带(n = 37)治疗。每组中的大多数患者因尿失禁原因接受了耻骨后根治性前列腺切除术和/或体外照射放疗(EBRT)。两组各有1例患者仅因该原因接受了EBRT。尿失禁的平均持续时间分别为4.2年和4.4年。胶原蛋白注射在区域麻醉或全身麻醉下经尿道进行,直至观察到黏膜贴合。男性吊带在脊髓麻醉下使用骨钻,采用可吸收或合成材料放置。回顾性地评估所有患者的控尿状态和与手术相关的发病率(如有)。还比较了两种手术的结果与尿失禁程度。

结果

胶原蛋白组中有10例(30%)患者在注射后显示出显著改善或治愈。术前,胶原蛋白组平均每天使用尿垫4.5片(标准差2.8),而注射后为2.2片(标准差1.1)。24例(70%)患者胶原蛋白注射失败。接受男性吊带治疗的患者术前平均每天使用尿垫3.7片(标准差1.5),术后该数字降至1.6片(标准差1.2)。该组中的大多数患者完全干爽或有显著改善(人数:28例,76%)。两组在成功率方面存在统计学显著差异(P < 0.05)。对治疗结果与尿失禁程度的分析表明,男性吊带对轻度至中度尿失禁患者最有效。

结论

我们的结果表明,男性吊带作为一种微创手术,在治疗男性轻至中度SUI方面比胶原蛋白植入更有效。

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