Tükel Raşit, Oflaz Serap Batmaz, Ozyildirim Ilker, Aslantaş Banu, Ertekin Erhan, Sözen Atiye, Alyanak Filiz, Atli Hatice
Istanbul Faculty of Medicine, Department of Psychiatry, Istanbul University, Istanbul, Turkey.
Depress Anxiety. 2007;24(4):251-5. doi: 10.1002/da.20234.
Our objective in this study was to compare the demographics and clinical characteristics of patients with episodic and chronic obsessive-compulsive disorder (OCD). We recruited 128 outpatients with a primary diagnosis of OCD according to DSM-IV diagnostic criteria. The episodic (n=24) and chronic (n=104) OCD patient groups were compared with respect to demographic variables and scores from various psychiatric rating scales. The severity of compulsions was found to be significantly lower in the episodic OCD group than in the chronic OCD group. When the frequency of Axis I disorders was assessed in the two groups, bipolar disorder was found to have a significantly higher prevalence rate in the episodic OCD group than that in the chronic OCD group. The results of our study point to the possibility of an association between a subgroup of OCD with an episodic course and bipolar disorder. The evidence of such a relationship, which needs to be confirmed in a larger sample, might expand the scope of the clinical assessment and therapy of this subgroup of OCD.
本研究的目的是比较发作性和慢性强迫症（OCD）患者的人口统计学特征和临床特征。我们根据《精神疾病诊断与统计手册》第四版（DSM-IV）诊断标准招募了128例初步诊断为强迫症的门诊患者。对发作性（n = 24）和慢性（n = 104）强迫症患者组的人口统计学变量和各种精神科评定量表的得分进行了比较。结果发现，发作性强迫症组的强迫行为严重程度显著低于慢性强迫症组。在评估两组中轴I障碍的发生率时，发现双相情感障碍在发作性强迫症组中的患病率显著高于慢性强迫症组。我们的研究结果表明，发作性病程的强迫症亚组与双相情感障碍之间可能存在关联。这种关系的证据需要在更大的样本中得到证实，这可能会扩大该强迫症亚组的临床评估和治疗范围。
