共表达基因查找器：一种用于寻找共表达基因群组的新算法。
Coexpressionfinder: a new algorithm for finding groups of coexpressed genes.
作者信息
Rogov Sergey I, Momynaliev Kuvat T, Govorun Vadim M
机构信息
Laboratory of Post-Genome Methods in Biology, Department of Molecular Biology and Genetics, Research Institute of Physico-Chemical Medicine, M.Pirogovskaya 1a, Moscow, Russia.
出版信息
J Bioinform Comput Biol. 2006 Aug;4(4):853-64. doi: 10.1142/s0219720006002193.
RESULTS
A new algorithm is developed which is intended to find groups of genes whose expression values change in a concordant manner in a series of experiments with DNA arrays. This algorithm is named as CoexpressionFinder. It can find more complete and internally coordinated groups of gene expression vectors than hierarchical clustering. Also, it finds more genes having coordinated expression. The algorithm's design allows parallel execution.
AVAILABILITY
The algorithm is implemented as a Java application which is freely available at: http://www.bioinformatics.ru/cf/index.jsp and http://bioinformatics.ru/cf/index.jsp.
结果
开发了一种新算法，旨在寻找在一系列DNA阵列实验中其表达值以一致方式变化的基因群。该算法被命名为共表达发现器（CoexpressionFinder）。与层次聚类相比，它能找到更完整且内部协调的基因表达载体组。此外，它还能找到更多具有协调表达的基因。该算法的设计允许并行执行。
可用性
该算法作为一个Java应用程序实现，可在以下网址免费获取：http://www.bioinformatics.ru/cf/index.jsp和http://bioinformatics.ru/cf/index.jsp。
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