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[危险饮酒者中的胃食管反流病]

[Gastroesophageal reflux disease in hazardous drinkers].

作者信息

Boguradzka Anna, Tarnowski Wiesław, Mazurczak-Pluta Teresa

机构信息

Centrum Medyczne Kształcenia Podyplomowego w Warszawie, Ośrodek Kształcenia Lekarzy Rodzinnych.

出版信息

Pol Merkur Lekarski. 2006 Jul;21(121):99-104.

Abstract

Excess alcohol consumption has been associated with multiple pathologies of the gastrointestinal tract. The consumption of large amounts of alcohol (hazardous drinking) facilitates acid regurgitation by reducing the pressure of the lower oesophageal sphincter and slowing both oesophageal motility and gastric emptying. Regardless of the type of alcoholic beverage involved lower alcohol doses also have been shown to induce decreased pressure in lower oesophageal, decrease in oesophageal motility and enhanced risk of gastroesophageal reflux disease (GERD). GERD can be important risk factor for oesophageal adenocarcinoma. For identification of hazardous drinking patients we can use AUDIT (Alcohol Use Disorder Identification Test). AUDIT has been created by World Health Organization experts as a simple screening test looking for hazardous drinking people.

摘要

过量饮酒与胃肠道的多种病变有关。大量饮酒(危险饮酒)会通过降低食管下括约肌压力、减缓食管蠕动和胃排空来促进胃酸反流。无论涉及何种酒精饮料,较低剂量的酒精也已被证明会导致食管下段压力降低、食管蠕动减弱以及胃食管反流病(GERD)风险增加。GERD可能是食管腺癌的重要危险因素。为了识别危险饮酒患者,我们可以使用AUDIT(酒精使用障碍识别测试)。AUDIT是由世界卫生组织专家创建的一种简单筛查测试,用于寻找危险饮酒者。

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