Izzard Mark, McIvor Nicholas, Chaplin John, Ianovski Ilia
Department of Head and Neck/ENT surgery, Auckland City Hospital, Auckland, New Zealand.
ANZ J Surg. 2006 Oct;76(10):953-6. doi: 10.1111/j.1445-2197.2006.03898.x.
Three cases of occult metastatic thyroid carcinoma presenting with neurological deficits are reviewed. In each case the patient's initial presentation was with symptoms of neurological deficiency secondary to a spinal cord compression. All patients received a combination of surgery, external beam radiotherapy and postoperative thyroxine treatment. Two of the three patients are alive and well, able to mobilize with minor neurological dysfunction. The diagnosis and management of the patients, as well as their outcomes are reviewed, with a discussion on further management issues alongside a review of the current published work.
本文回顾了三例隐匿性转移性甲状腺癌伴神经功能缺损的病例。在每例病例中,患者最初的表现均为继发于脊髓压迫的神经功能缺损症状。所有患者均接受了手术、外照射放疗及术后甲状腺素治疗的联合治疗。三名患者中有两名存活且状况良好,虽有轻微神经功能障碍但能够活动。本文对这些患者的诊断、治疗及预后进行了回顾,并结合当前已发表的研究讨论了进一步的治疗问题。